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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARD11
All Species:
18.18
Human Site:
S433
Identified Species:
50
UniProt:
Q9BXL7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXL7
NP_115791.3
1154
133284
S433
A
C
I
V
N
L
E
S
K
L
R
R
L
S
K
Chimpanzee
Pan troglodytes
XP_518943
1268
145477
S433
A
C
I
V
N
L
E
S
K
L
R
R
L
S
K
Rhesus Macaque
Macaca mulatta
XP_001104636
1259
144246
S538
A
C
I
V
N
L
E
S
K
L
R
R
L
S
K
Dog
Lupus familis
XP_547005
1188
137018
S467
A
C
I
V
N
L
E
S
K
L
R
R
L
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIS0
1159
134022
S433
A
C
I
V
N
L
E
S
K
L
R
R
L
S
K
Rat
Rattus norvegicus
Q9EPY0
536
62613
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510375
817
92558
Q156
L
R
V
Q
R
K
G
Q
L
Q
K
E
Q
Q
L
Chicken
Gallus gallus
NP_001006161
1170
134805
C435
A
C
I
V
N
L
E
C
K
L
R
R
L
S
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685144
1357
154601
E618
E
A
K
I
V
N
L
E
C
K
L
R
R
M
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.6
87.9
91.3
N.A.
91.8
24.1
N.A.
31.2
78.6
N.A.
54.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.8
89.3
94.2
N.A.
95.5
33
N.A.
46
88.7
N.A.
66.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
93.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
13.3
93.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% A
% Cys:
0
67
0
0
0
0
0
12
12
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
12
0
0
0
0
0
67
12
0
0
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
67
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
12
0
0
67
12
12
0
0
0
67
% K
% Leu:
12
0
0
0
0
67
12
0
12
67
12
0
67
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
0
0
67
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
12
0
0
0
12
0
12
0
0
12
12
0
% Q
% Arg:
0
12
0
0
12
0
0
0
0
0
67
78
12
0
0
% R
% Ser:
0
0
0
0
0
0
0
56
0
0
0
0
0
67
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
12
67
12
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _