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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDCA4
All Species:
11.82
Human Site:
S144
Identified Species:
32.5
UniProt:
Q9BXL8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXL8
NP_060425.2
241
26114
S144
A
P
R
H
L
Q
S
S
A
W
E
M
D
G
P
Chimpanzee
Pan troglodytes
XP_510205
241
26065
S144
A
P
R
H
L
Q
S
S
A
W
E
M
D
G
P
Rhesus Macaque
Macaca mulatta
XP_001096509
166
17617
D76
I
Q
E
E
M
T
Q
D
G
T
W
R
A
V
A
Dog
Lupus familis
XP_855522
242
25885
S144
A
L
R
S
P
Q
S
S
L
W
E
V
D
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWM2
237
26089
S140
G
Q
R
N
P
Q
S
S
L
W
E
M
D
S
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507850
246
27592
N148
N
A
R
N
P
P
S
N
V
W
E
M
E
S
P
Chicken
Gallus gallus
NP_001026383
249
28005
N151
A
L
R
N
L
Q
S
N
V
W
E
M
E
N
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001008580
286
31346
D185
G
D
D
D
E
E
I
D
T
E
D
E
S
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783091
346
37757
S235
N
I
K
Q
E
I
N
S
C
L
D
M
T
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
65.9
73.5
N.A.
73.4
N.A.
N.A.
64.2
62.2
N.A.
44.4
N.A.
N.A.
N.A.
N.A.
28.6
Protein Similarity:
100
99.5
67.2
78
N.A.
78
N.A.
N.A.
74.8
75
N.A.
58.7
N.A.
N.A.
N.A.
N.A.
39.8
P-Site Identity:
100
100
0
53.3
N.A.
60
N.A.
N.A.
40
53.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
6.6
60
N.A.
66.6
N.A.
N.A.
60
73.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
12
0
0
0
0
0
0
23
0
0
0
12
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
12
12
12
0
0
0
23
0
0
23
0
45
0
0
% D
% Glu:
0
0
12
12
23
12
0
0
0
12
67
12
23
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
23
0
0
0
0
0
0
0
12
0
0
0
0
23
0
% G
% His:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
12
0
0
0
12
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
23
0
0
34
0
0
0
23
12
0
0
0
0
0
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
67
0
0
0
% M
% Asn:
23
0
0
34
0
0
12
23
0
0
0
0
0
12
0
% N
% Pro:
0
23
0
0
34
12
0
0
0
0
0
0
0
0
56
% P
% Gln:
0
23
0
12
0
56
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
67
0
0
0
0
0
0
0
0
12
0
0
0
% R
% Ser:
0
0
0
12
0
0
67
56
0
0
0
0
12
34
23
% S
% Thr:
0
0
0
0
0
12
0
0
12
12
0
0
12
12
12
% T
% Val:
0
0
0
0
0
0
0
0
23
0
0
12
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
67
12
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _