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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PINK1
All Species:
9.09
Human Site:
S225
Identified Species:
20
UniProt:
Q9BXM7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXM7
NP_115785.1
581
62769
S225
I
K
M
M
W
N
I
S
A
G
S
S
S
E
A
Chimpanzee
Pan troglodytes
XP_001164912
491
52307
A156
R
Q
S
V
A
G
L
A
A
R
L
Q
R
Q
F
Rhesus Macaque
Macaca mulatta
XP_001096957
581
63018
S225
I
K
M
M
W
N
I
S
A
G
S
S
S
E
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q99MQ3
580
63162
S224
I
K
M
M
W
N
I
S
A
G
S
S
S
E
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517392
268
28900
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001008628
574
63728
G212
M
K
M
M
W
N
I
G
A
G
S
S
S
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572340
721
80209
D343
L
K
M
M
F
N
Y
D
I
Q
S
N
A
L
S
Honey Bee
Apis mellifera
XP_623327
614
69709
D224
L
K
M
M
F
N
Y
D
A
E
S
N
A
L
S
Nematode Worm
Caenorhab. elegans
Q09298
641
73035
E205
I
K
L
M
F
N
F
E
H
D
R
D
G
D
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
V146
D
F
E
V
L
K
V
V
G
Q
G
A
F
G
K
Baker's Yeast
Sacchar. cerevisiae
P24719
497
56831
D159
M
G
F
L
R
E
V
D
Q
W
E
I
T
N
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.8
97.2
N.A.
N.A.
81.4
N.A.
N.A.
21
N.A.
N.A.
54.5
N.A.
28.8
34
27.6
N.A.
Protein Similarity:
100
69.5
97.9
N.A.
N.A.
87.4
N.A.
N.A.
30.6
N.A.
N.A.
67.3
N.A.
43
50.4
42.9
N.A.
P-Site Identity:
100
6.6
100
N.A.
N.A.
100
N.A.
N.A.
0
N.A.
N.A.
80
N.A.
33.3
40
33.3
N.A.
P-Site Similarity:
100
40
100
N.A.
N.A.
100
N.A.
N.A.
0
N.A.
N.A.
93.3
N.A.
66.6
73.3
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.3
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
55
0
0
10
19
0
46
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
28
0
10
0
10
0
19
0
% D
% Glu:
0
0
10
0
0
10
0
10
0
10
10
0
0
28
0
% E
% Phe:
0
10
10
0
28
0
10
0
0
0
0
0
10
0
10
% F
% Gly:
0
10
0
0
0
10
0
10
10
37
10
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
37
0
0
0
0
0
37
0
10
0
0
10
0
0
0
% I
% Lys:
0
64
0
0
0
10
0
0
0
0
0
0
0
0
10
% K
% Leu:
19
0
10
10
10
0
10
0
0
0
10
0
0
19
0
% L
% Met:
19
0
55
64
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
64
0
0
0
0
0
19
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
19
0
10
0
10
0
% Q
% Arg:
10
0
0
0
10
0
0
0
0
10
10
0
10
0
10
% R
% Ser:
0
0
10
0
0
0
0
28
0
0
55
37
37
0
19
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
19
0
0
19
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
37
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _