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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PINK1 All Species: 8.48
Human Site: S477 Identified Species: 18.67
UniProt: Q9BXM7 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BXM7 NP_115785.1 581 62769 S477 Q L P A L P E S V P P D V R Q
Chimpanzee Pan troglodytes XP_001164912 491 52307 N398 T L F L V M K N Y P C T L R Q
Rhesus Macaque Macaca mulatta XP_001096957 581 63018 S477 Q L P A L P E S V P P D V R Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q99MQ3 580 63162 S476 Q L P E M P E S V P P E A R R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517392 268 28900 R178 H A T S R M P R E A V V Q A A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001008628 574 63728 V464 P A A A P D D V Q L V V K L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572340 721 80209 R594 S L R N S D Y R Q D Q L P P M
Honey Bee Apis mellifera XP_623327 614 69709 N477 K D L L P L P N N I P T I I S
Nematode Worm Caenorhab. elegans Q09298 641 73035 V452 L P S R V N F V A R D V I F D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39030 471 53019 L367 S N E A H A L L K G L L Q K E
Baker's Yeast Sacchar. cerevisiae P24719 497 56831 N397 S E R S I I Q N A K I G K L N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.8 97.2 N.A. N.A. 81.4 N.A. N.A. 21 N.A. N.A. 54.5 N.A. 28.8 34 27.6 N.A.
Protein Similarity: 100 69.5 97.9 N.A. N.A. 87.4 N.A. N.A. 30.6 N.A. N.A. 67.3 N.A. 43 50.4 42.9 N.A.
P-Site Identity: 100 26.6 100 N.A. N.A. 66.6 N.A. N.A. 0 N.A. N.A. 6.6 N.A. 6.6 6.6 0 N.A.
P-Site Similarity: 100 53.3 100 N.A. N.A. 86.6 N.A. N.A. 6.6 N.A. N.A. 13.3 N.A. 6.6 26.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.5 20.6 N.A.
Protein Similarity: N.A. N.A. N.A. 37.3 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 10 37 0 10 0 0 19 10 0 0 10 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 10 0 0 0 19 10 0 0 10 10 19 0 0 10 % D
% Glu: 0 10 10 10 0 0 28 0 10 0 0 10 0 0 10 % E
% Phe: 0 0 10 0 0 0 10 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % G
% His: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 10 0 0 0 10 10 0 19 10 0 % I
% Lys: 10 0 0 0 0 0 10 0 10 10 0 0 19 10 0 % K
% Leu: 10 46 10 19 19 10 10 10 0 10 10 19 10 19 10 % L
% Met: 0 0 0 0 10 19 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 10 0 10 0 10 0 28 10 0 0 0 0 0 10 % N
% Pro: 10 10 28 0 19 28 19 0 0 37 37 0 10 10 0 % P
% Gln: 28 0 0 0 0 0 10 0 19 0 10 0 19 0 28 % Q
% Arg: 0 0 19 10 10 0 0 19 0 10 0 0 0 37 10 % R
% Ser: 28 0 10 19 10 0 0 28 0 0 0 0 0 0 10 % S
% Thr: 10 0 10 0 0 0 0 0 0 0 0 19 0 0 0 % T
% Val: 0 0 0 0 19 0 0 19 28 0 19 28 19 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _