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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PINK1
All Species:
13.64
Human Site:
S499
Identified Species:
30
UniProt:
Q9BXM7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXM7
NP_115785.1
581
62769
S499
R
E
A
S
K
R
P
S
A
R
V
A
A
N
V
Chimpanzee
Pan troglodytes
XP_001164912
491
52307
A418
T
P
S
P
R
L
A
A
M
M
L
L
Q
L
L
Rhesus Macaque
Macaca mulatta
XP_001096957
581
63018
S499
R
E
A
S
K
R
P
S
A
R
V
A
A
N
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q99MQ3
580
63162
S498
R
E
A
S
K
R
P
S
A
R
L
A
A
N
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517392
268
28900
D197
F
R
A
V
G
P
G
D
G
T
G
R
E
S
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001008628
574
63728
A486
R
P
S
A
R
V
A
A
N
I
L
H
I
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572340
721
80209
S626
P
N
P
S
K
R
V
S
P
D
I
A
A
N
V
Honey Bee
Apis mellifera
XP_623327
614
69709
A505
R
L
D
T
E
T
A
A
T
I
V
Q
L
H
L
Nematode Worm
Caenorhab. elegans
Q09298
641
73035
T502
K
C
G
I
S
Q
M
T
T
L
L
A
G
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
A386
L
G
S
G
P
S
G
A
E
E
I
K
K
H
K
Baker's Yeast
Sacchar. cerevisiae
P24719
497
56831
N416
Q
W
D
I
V
S
D
N
A
K
S
F
V
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.8
97.2
N.A.
N.A.
81.4
N.A.
N.A.
21
N.A.
N.A.
54.5
N.A.
28.8
34
27.6
N.A.
Protein Similarity:
100
69.5
97.9
N.A.
N.A.
87.4
N.A.
N.A.
30.6
N.A.
N.A.
67.3
N.A.
43
50.4
42.9
N.A.
P-Site Identity:
100
0
100
N.A.
N.A.
93.3
N.A.
N.A.
6.6
N.A.
N.A.
6.6
N.A.
53.3
13.3
6.6
N.A.
P-Site Similarity:
100
33.3
100
N.A.
N.A.
100
N.A.
N.A.
13.3
N.A.
N.A.
53.3
N.A.
60
46.6
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.3
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
37
10
0
0
28
37
37
0
0
46
37
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
0
0
10
10
0
10
0
0
0
0
10
% D
% Glu:
0
28
0
0
10
0
0
0
10
10
0
0
10
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
10
10
10
10
0
19
0
10
0
10
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
19
0
% H
% Ile:
0
0
0
19
0
0
0
0
0
19
19
0
10
0
0
% I
% Lys:
10
0
0
0
37
0
0
0
0
10
0
10
10
10
10
% K
% Leu:
10
10
0
0
0
10
0
0
0
10
37
10
10
10
28
% L
% Met:
0
0
0
0
0
0
10
0
10
10
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
10
10
0
0
0
0
37
0
% N
% Pro:
10
19
10
10
10
10
28
0
10
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
10
0
0
0
0
0
10
10
0
0
% Q
% Arg:
46
10
0
0
19
37
0
0
0
28
0
10
0
0
0
% R
% Ser:
0
0
28
37
10
19
0
37
0
0
10
0
0
28
10
% S
% Thr:
10
0
0
10
0
10
0
10
19
10
0
0
0
0
0
% T
% Val:
0
0
0
10
10
10
10
0
0
0
28
0
10
0
37
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _