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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PINK1
All Species:
5.15
Human Site:
T22
Identified Species:
11.33
UniProt:
Q9BXM7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXM7
NP_115785.1
581
62769
T22
R
A
L
L
L
R
F
T
G
K
P
G
R
A
Y
Chimpanzee
Pan troglodytes
XP_001164912
491
52307
T12
K
C
Q
F
P
F
S
T
S
R
F
C
P
G
P
Rhesus Macaque
Macaca mulatta
XP_001096957
581
63018
T22
R
E
L
L
L
R
F
T
G
K
P
G
R
A
Y
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q99MQ3
580
63162
A22
R
A
L
L
L
R
F
A
P
K
P
G
P
L
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517392
268
28900
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001008628
574
63728
A26
Q
L
G
L
L
K
P
A
G
R
V
A
A
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572340
721
80209
C22
R
Y
I
L
R
S
Y
C
K
R
D
I
H
A
N
Honey Bee
Apis mellifera
XP_623327
614
69709
V42
N
Y
H
D
K
I
H
V
V
Q
V
G
K
S
Q
Nematode Worm
Caenorhab. elegans
Q09298
641
73035
G22
N
E
L
V
A
K
G
G
R
L
P
I
F
Q
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
A9
V
S
S
Q
C
S
V
A
N
K
N
Q
T
G
K
Baker's Yeast
Sacchar. cerevisiae
P24719
497
56831
K12
Y
S
C
N
L
A
T
K
D
D
I
E
M
A
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.8
97.2
N.A.
N.A.
81.4
N.A.
N.A.
21
N.A.
N.A.
54.5
N.A.
28.8
34
27.6
N.A.
Protein Similarity:
100
69.5
97.9
N.A.
N.A.
87.4
N.A.
N.A.
30.6
N.A.
N.A.
67.3
N.A.
43
50.4
42.9
N.A.
P-Site Identity:
100
6.6
93.3
N.A.
N.A.
66.6
N.A.
N.A.
0
N.A.
N.A.
20
N.A.
20
6.6
13.3
N.A.
P-Site Similarity:
100
20
93.3
N.A.
N.A.
73.3
N.A.
N.A.
0
N.A.
N.A.
46.6
N.A.
40
26.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.3
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
10
10
0
28
0
0
0
10
10
37
0
% A
% Cys:
0
10
10
0
10
0
0
10
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
10
10
10
0
0
0
0
% D
% Glu:
0
19
0
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
10
0
10
28
0
0
0
10
0
10
0
19
% F
% Gly:
0
0
10
0
0
0
10
10
28
0
0
37
0
19
10
% G
% His:
0
0
10
0
0
0
10
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
10
19
0
0
0
% I
% Lys:
10
0
0
0
10
19
0
10
10
37
0
0
10
10
10
% K
% Leu:
0
10
37
46
46
0
0
0
0
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
19
0
0
10
0
0
0
0
10
0
10
0
0
0
10
% N
% Pro:
0
0
0
0
10
0
10
0
10
0
37
0
19
0
10
% P
% Gln:
10
0
10
10
0
0
0
0
0
10
0
10
0
10
10
% Q
% Arg:
37
0
0
0
10
28
0
0
10
28
0
0
19
0
10
% R
% Ser:
0
19
10
0
0
19
10
0
10
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
10
28
0
0
0
0
10
0
0
% T
% Val:
10
0
0
10
0
0
10
10
10
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
19
0
0
0
0
10
0
0
0
0
0
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _