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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PINK1
All Species:
10
Human Site:
Y466
Identified Species:
22
UniProt:
Q9BXM7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXM7
NP_115785.1
581
62769
Y466
A
H
L
E
S
R
S
Y
Q
E
A
Q
L
P
A
Chimpanzee
Pan troglodytes
XP_001164912
491
52307
G387
R
L
H
P
E
G
L
G
H
G
R
T
L
F
L
Rhesus Macaque
Macaca mulatta
XP_001096957
581
63018
Y466
A
H
L
E
S
R
S
Y
Q
E
A
Q
L
P
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q99MQ3
580
63162
Y465
A
H
L
E
S
R
S
Y
Q
E
A
Q
L
P
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517392
268
28900
P167
V
Q
E
H
T
S
S
P
S
P
P
H
A
T
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001008628
574
63728
L453
R
S
Y
Q
E
K
Q
L
P
A
L
P
A
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572340
721
80209
E583
G
M
A
R
E
R
G
E
M
T
L
S
L
R
N
Honey Bee
Apis mellifera
XP_623327
614
69709
N466
G
T
S
L
K
N
Y
N
Y
N
E
K
D
L
L
Nematode Worm
Caenorhab. elegans
Q09298
641
73035
E441
T
A
T
Y
Q
E
S
E
L
P
A
L
P
S
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
P356
V
K
D
K
I
K
L
P
Q
F
L
S
N
E
A
Baker's Yeast
Sacchar. cerevisiae
P24719
497
56831
Y386
L
T
G
I
S
P
F
Y
G
D
G
S
E
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.8
97.2
N.A.
N.A.
81.4
N.A.
N.A.
21
N.A.
N.A.
54.5
N.A.
28.8
34
27.6
N.A.
Protein Similarity:
100
69.5
97.9
N.A.
N.A.
87.4
N.A.
N.A.
30.6
N.A.
N.A.
67.3
N.A.
43
50.4
42.9
N.A.
P-Site Identity:
100
6.6
100
N.A.
N.A.
93.3
N.A.
N.A.
6.6
N.A.
N.A.
6.6
N.A.
13.3
0
13.3
N.A.
P-Site Similarity:
100
6.6
100
N.A.
N.A.
93.3
N.A.
N.A.
20
N.A.
N.A.
20
N.A.
13.3
6.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.3
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
10
10
0
0
0
0
0
0
10
37
0
19
10
37
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
10
0
0
10
0
0
% D
% Glu:
0
0
10
28
28
10
0
19
0
28
10
0
10
10
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
10
0
0
0
10
0
% F
% Gly:
19
0
10
0
0
10
10
10
10
10
10
0
0
0
0
% G
% His:
0
28
10
10
0
0
0
0
10
0
0
10
0
0
0
% H
% Ile:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
10
10
19
0
0
0
0
0
10
0
0
0
% K
% Leu:
10
10
28
10
0
0
19
10
10
0
28
10
46
10
19
% L
% Met:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
10
0
0
10
0
10
% N
% Pro:
0
0
0
10
0
10
0
19
10
19
10
10
10
28
0
% P
% Gln:
0
10
0
10
10
0
10
0
37
0
0
28
0
0
0
% Q
% Arg:
19
0
0
10
0
37
0
0
0
0
10
0
0
19
10
% R
% Ser:
0
10
10
0
37
10
46
0
10
0
0
28
0
10
19
% S
% Thr:
10
19
10
0
10
0
0
0
0
10
0
10
0
10
0
% T
% Val:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
0
0
10
37
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _