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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM59
All Species:
31.52
Human Site:
S275
Identified Species:
77.04
UniProt:
Q9BXS4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXS4
NP_004863.2
323
36223
S275
Y
V
P
S
E
K
L
S
I
Y
G
D
L
E
F
Chimpanzee
Pan troglodytes
XP_001150662
323
36223
S275
Y
V
P
S
E
K
L
S
I
Y
G
D
L
E
F
Rhesus Macaque
Macaca mulatta
XP_001113536
323
36181
S275
Y
V
P
S
E
K
L
S
I
Y
G
D
L
E
F
Dog
Lupus familis
XP_536700
334
37411
S286
Y
V
P
S
E
K
L
S
I
Y
G
D
L
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY73
323
36295
S275
Y
V
P
P
E
K
L
S
I
Y
G
D
L
E
F
Rat
Rattus norvegicus
Q5HZE8
331
36958
C276
I
I
L
W
L
S
C
C
T
L
V
T
T
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509156
510
53877
D418
G
S
D
P
D
N
L
D
S
H
S
D
P
G
E
Chicken
Gallus gallus
NP_001006541
325
36152
S277
Y
V
P
S
E
K
L
S
I
Y
G
D
L
E
Y
Frog
Xenopus laevis
NP_001085961
324
36062
S276
Y
I
P
S
E
K
L
S
I
Y
G
D
L
E
F
Zebra Danio
Brachydanio rerio
NP_001104658
330
37576
S282
Y
V
P
A
E
K
L
S
I
Y
G
D
M
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99
93.1
N.A.
94.1
29.9
N.A.
20
78.7
60.7
60.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
99.3
95.5
N.A.
97.5
45.3
N.A.
30
85.8
73.7
74.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
13.3
93.3
93.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
6.6
N.A.
26.6
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
10
0
0
0
90
0
0
0
% D
% Glu:
0
0
0
0
80
0
0
0
0
0
0
0
0
80
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
80
0
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
10
20
0
0
0
0
0
0
80
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
80
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
10
0
90
0
0
10
0
0
70
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
80
20
0
0
0
0
0
0
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
60
0
10
0
80
10
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
10
10
0
0
% T
% Val:
0
70
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
80
0
0
0
0
0
0
0
0
80
0
0
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _