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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOV10L1 All Species: 2.12
Human Site: S1194 Identified Species: 3.89
UniProt: Q9BXT6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BXT6 NP_061868.1 1211 135293 S1194 G E G V A D P S Y P V V P E S
Chimpanzee Pan troglodytes XP_513630 1028 116494 G1012 Y L P Q E R E G E G G L S L Q
Rhesus Macaque Macaca mulatta XP_001116215 460 50544 Y444 D G V A E P S Y P V V P E S T
Dog Lupus familis XP_531690 1185 132118 V1168 E Y S I T N G V Y T G C N L P
Cat Felis silvestris
Mouse Mus musculus Q99MV5 1187 132773 G1171 L E Y S V S N G V Y T G C D L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513658 1513 167007 A1295 G G T E G A K A S R K L H S L
Chicken Gallus gallus Q5ZKD7 967 109032 P951 Y P Y E E E P P E E D S L A N
Frog Xenopus laevis Q8QHA5 1053 119713 E1037 L I C N L K T E N Q I Y D L P
Zebra Danio Brachydanio rerio Q1LXK4 1013 116388 E997 Q E I T V E T E E S V V Q Q F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q6J5K9 1274 144870 V1256 V I N Q K D E V P V C L E T F
Honey Bee Apis mellifera XP_001121242 1059 120277 S1043 G F S N M E D S W I E A N N S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795541 2020 222948 D1319 G Q Q G E E K D G D E E E S I
Poplar Tree Populus trichocarpa XP_002332671 894 100931 Q878 H P G S S Q A Q I P E P V T D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.7 20.2 80.4 N.A. 76.7 N.A. N.A. 53.4 30 20.4 30.7 N.A. 25.2 27 N.A. 24.1
Protein Similarity: 100 46.6 28.2 87.1 N.A. 83.8 N.A. N.A. 64.4 45.5 38.4 47.4 N.A. 44.8 44 N.A. 35
P-Site Identity: 100 0 6.6 6.6 N.A. 6.6 N.A. N.A. 6.6 6.6 0 20 N.A. 6.6 20 N.A. 6.6
P-Site Similarity: 100 6.6 13.3 20 N.A. 13.3 N.A. N.A. 20 20 6.6 33.3 N.A. 13.3 33.3 N.A. 20
Percent
Protein Identity: 31.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 46.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 20 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 8 8 8 0 0 0 8 0 8 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 8 8 8 0 0 % C
% Asp: 8 0 0 0 0 16 8 8 0 8 8 0 8 8 8 % D
% Glu: 8 24 0 16 31 31 16 16 24 8 24 8 24 8 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 16 % F
% Gly: 31 16 16 8 8 0 8 16 8 8 16 8 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 16 8 8 0 0 0 0 8 8 8 0 0 0 8 % I
% Lys: 0 0 0 0 8 8 16 0 0 0 8 0 0 0 0 % K
% Leu: 16 8 0 0 8 0 0 0 0 0 0 24 8 24 16 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 16 0 8 8 0 8 0 0 0 16 8 8 % N
% Pro: 0 16 8 0 0 8 16 8 16 16 0 16 8 0 16 % P
% Gln: 8 8 8 16 0 8 0 8 0 8 0 0 8 8 8 % Q
% Arg: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % R
% Ser: 0 0 16 16 8 8 8 16 8 8 0 8 8 24 16 % S
% Thr: 0 0 8 8 8 0 16 0 0 8 8 0 0 16 8 % T
% Val: 8 0 8 8 16 0 0 16 8 16 24 16 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 16 8 16 0 0 0 0 8 16 8 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _