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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OSBPL1A
All Species:
18.48
Human Site:
S378
Identified Species:
36.97
UniProt:
Q9BXW6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXW6
NP_060500.3
950
108470
S378
Q
R
L
D
R
E
I
S
N
F
L
K
M
I
K
Chimpanzee
Pan troglodytes
XP_523889
950
108480
S378
Q
R
L
D
R
E
I
S
N
F
L
K
M
I
K
Rhesus Macaque
Macaca mulatta
XP_001096083
926
105850
D357
E
D
M
V
S
A
V
D
L
K
K
S
L
E
K
Dog
Lupus familis
XP_537881
950
108558
S378
Q
K
L
D
R
E
I
S
N
F
L
K
M
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91XL9
950
107777
Y378
Q
R
L
D
R
E
I
Y
N
F
L
K
M
I
K
Rat
Rattus norvegicus
Q8K4M9
950
107747
Y378
Q
R
L
D
R
E
I
Y
N
F
L
K
M
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505777
479
55160
Chicken
Gallus gallus
XP_419165
954
108160
E380
C
Q
Q
R
L
S
K
E
I
S
D
F
L
A
M
Frog
Xenopus laevis
NP_001080312
475
54651
Zebra Danio
Brachydanio rerio
NP_001038547
967
110079
L382
Q
R
L
E
K
E
V
L
S
L
L
S
M
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786375
1117
125578
R488
T
L
K
N
A
Q
T
R
H
H
L
V
E
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35845
1188
135079
Y520
I
P
S
D
D
E
G
Y
S
E
D
D
S
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.5
95.1
N.A.
92
92
N.A.
37.5
81.7
36.8
68
N.A.
N.A.
N.A.
N.A.
34.9
Protein Similarity:
100
99.6
96.7
98
N.A.
96.3
96
N.A.
44.3
91.5
43.7
82.3
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
93.3
N.A.
0
0
0
46.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
33.3
100
N.A.
93.3
93.3
N.A.
0
13.3
0
80
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
9
0
0
0
0
0
0
0
9
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
50
9
0
0
9
0
0
17
9
0
9
9
% D
% Glu:
9
0
0
9
0
59
0
9
0
9
0
0
9
17
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
42
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
42
0
9
0
0
0
0
42
0
% I
% Lys:
0
9
9
0
9
0
9
0
0
9
9
42
0
0
59
% K
% Leu:
0
9
50
0
9
0
0
9
9
9
59
0
17
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
50
0
9
% M
% Asn:
0
0
0
9
0
0
0
0
42
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
50
9
9
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
42
0
9
42
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
0
9
9
0
25
17
9
0
17
9
0
9
% S
% Thr:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
17
0
0
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _