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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OSBPL1A
All Species:
34.55
Human Site:
S890
Identified Species:
69.09
UniProt:
Q9BXW6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXW6
NP_060500.3
950
108470
S890
N
G
E
I
D
Q
A
S
E
E
K
K
R
L
E
Chimpanzee
Pan troglodytes
XP_523889
950
108480
S890
N
G
E
I
D
Q
A
S
E
E
K
K
R
L
E
Rhesus Macaque
Macaca mulatta
XP_001096083
926
105850
S866
N
G
E
I
D
Q
A
S
E
E
K
K
R
L
E
Dog
Lupus familis
XP_537881
950
108558
S890
N
G
E
I
D
Q
A
S
E
E
K
K
R
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91XL9
950
107777
S890
N
G
E
I
D
L
A
S
E
E
K
K
R
L
E
Rat
Rattus norvegicus
Q8K4M9
950
107747
S890
N
G
E
I
D
Q
A
S
E
E
K
K
R
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505777
479
55160
E423
D
L
A
S
Q
E
K
E
R
L
E
E
K
Q
R
Chicken
Gallus gallus
XP_419165
954
108160
S894
N
G
E
I
D
L
A
S
E
E
K
K
R
L
E
Frog
Xenopus laevis
NP_001080312
475
54651
E419
D
L
A
G
N
E
K
E
R
L
E
E
K
Q
R
Zebra Danio
Brachydanio rerio
NP_001038547
967
110079
S907
N
G
D
I
D
M
A
S
E
E
K
K
R
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786375
1117
125578
S1057
N
G
D
I
D
G
A
S
S
E
K
H
R
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35845
1188
135079
E1126
E
Y
D
K
A
A
A
E
K
H
R
V
E
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.5
95.1
N.A.
92
92
N.A.
37.5
81.7
36.8
68
N.A.
N.A.
N.A.
N.A.
34.9
Protein Similarity:
100
99.6
96.7
98
N.A.
96.3
96
N.A.
44.3
91.5
43.7
82.3
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
0
93.3
0
86.6
N.A.
N.A.
N.A.
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
33.3
93.3
40
93.3
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
9
9
84
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
25
0
75
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
59
0
0
17
0
25
67
75
17
17
9
0
75
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
75
0
9
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% H
% Ile:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
0
17
0
9
0
75
67
17
0
9
% K
% Leu:
0
17
0
0
0
17
0
0
0
17
0
0
0
75
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
75
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
42
0
0
0
0
0
0
0
17
0
% Q
% Arg:
0
0
0
0
0
0
0
0
17
0
9
0
75
0
17
% R
% Ser:
0
0
0
9
0
0
0
75
9
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _