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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OSBPL1A
All Species:
17.27
Human Site:
Y277
Identified Species:
34.55
UniProt:
Q9BXW6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXW6
NP_060500.3
950
108470
Y277
P
D
A
V
H
N
I
Y
R
Q
G
C
K
H
L
Chimpanzee
Pan troglodytes
XP_523889
950
108480
Y277
P
D
A
V
H
N
I
Y
R
Q
G
C
K
H
L
Rhesus Macaque
Macaca mulatta
XP_001096083
926
105850
V256
G
W
R
L
F
W
V
V
L
E
H
G
V
L
S
Dog
Lupus familis
XP_537881
950
108558
Y277
P
D
A
V
R
N
I
Y
R
Q
G
C
K
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91XL9
950
107777
Y277
P
D
A
V
H
N
S
Y
R
Q
G
C
K
H
L
Rat
Rattus norvegicus
Q8K4M9
950
107747
Y277
P
D
A
V
H
N
S
Y
R
Q
G
C
K
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505777
479
55160
Chicken
Gallus gallus
XP_419165
954
108160
H279
A
D
A
V
N
N
E
H
R
Q
G
C
K
H
L
Frog
Xenopus laevis
NP_001080312
475
54651
Zebra Danio
Brachydanio rerio
NP_001038547
967
110079
R281
D
A
D
S
N
T
R
R
Q
G
C
K
P
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786375
1117
125578
R387
L
Y
R
A
G
L
M
R
R
R
H
L
W
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35845
1188
135079
R419
N
L
H
A
T
S
K
R
L
T
K
S
P
H
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.5
95.1
N.A.
92
92
N.A.
37.5
81.7
36.8
68
N.A.
N.A.
N.A.
N.A.
34.9
Protein Similarity:
100
99.6
96.7
98
N.A.
96.3
96
N.A.
44.3
91.5
43.7
82.3
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
100
0
93.3
N.A.
93.3
93.3
N.A.
0
73.3
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
93.3
N.A.
0
86.6
0
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
50
17
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
50
0
0
0
% C
% Asp:
9
50
9
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
9
0
0
0
0
9
50
9
0
0
0
% G
% His:
0
0
9
0
34
0
0
9
0
0
17
0
0
59
0
% H
% Ile:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
9
9
50
0
0
% K
% Leu:
9
9
0
9
0
9
0
0
17
0
0
9
0
17
59
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
17
50
0
0
0
0
0
0
0
0
0
% N
% Pro:
42
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
50
0
0
0
0
0
% Q
% Arg:
0
0
17
0
9
0
9
25
59
9
0
0
0
0
0
% R
% Ser:
0
0
0
9
0
9
17
0
0
0
0
9
0
0
9
% S
% Thr:
0
0
0
0
9
9
0
0
0
9
0
0
0
0
9
% T
% Val:
0
0
0
50
0
0
9
9
0
0
0
0
9
9
9
% V
% Trp:
0
9
0
0
0
9
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
9
0
0
0
0
0
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _