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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCD2
All Species:
9.09
Human Site:
S178
Identified Species:
22.22
UniProt:
Q9BXW9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXW9
NP_001018125.1
1471
166462
S178
N
I
P
R
L
I
V
S
Q
L
K
W
L
D
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541774
1447
163939
S178
N
I
P
R
L
I
I
S
Q
L
K
W
L
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80V62
1450
163599
N176
N
M
A
R
L
I
I
N
Q
L
K
W
L
D
R
Rat
Rattus norvegicus
Q6IV68
1451
163602
S178
S
M
P
R
L
I
I
S
Q
L
K
W
L
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001034350
1439
160716
N181
N
F
P
R
L
I
V
N
Q
F
K
W
L
D
G
Frog
Xenopus laevis
NP_001089160
1443
162550
N180
S
I
P
R
L
I
I
N
Q
F
K
W
L
D
R
Zebra Danio
Brachydanio rerio
NP_958498
1445
161820
N177
N
V
P
R
L
I
V
N
Q
L
K
W
L
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996246
1478
167444
M186
N
F
L
M
I
D
F
M
R
D
A
C
V
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002308832
1476
164919
D193
D
V
A
R
L
I
I
D
Q
F
R
W
L
D
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193233
1489
166780
M188
H
V
F
T
D
K
L
M
Q
V
L
S
I
C
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
83.8
N.A.
72.6
74.3
N.A.
N.A.
55.5
57.2
52.8
N.A.
22.3
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
90.2
N.A.
82.3
83.4
N.A.
N.A.
71.6
72.8
69.8
N.A.
44
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
73.3
80
N.A.
N.A.
73.3
73.3
86.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
100
N.A.
N.A.
80
93.3
100
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
27.7
N.A.
N.A.
22.7
N.A.
N.A.
Protein Similarity:
48.3
N.A.
N.A.
43.3
N.A.
N.A.
P-Site Identity:
46.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% C
% Asp:
10
0
0
0
10
10
0
10
0
10
0
0
0
80
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
20
10
0
0
0
10
0
0
30
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
30
0
0
10
80
50
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
70
0
0
0
0
% K
% Leu:
0
0
10
0
80
0
10
0
0
50
10
0
80
0
0
% L
% Met:
0
20
0
10
0
0
0
20
0
0
0
0
0
0
0
% M
% Asn:
60
0
0
0
0
0
0
40
0
0
0
0
0
0
0
% N
% Pro:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
90
0
0
0
0
0
0
% Q
% Arg:
0
0
0
80
0
0
0
0
10
0
10
0
0
0
60
% R
% Ser:
20
0
0
0
0
0
0
30
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
30
0
0
0
0
30
0
0
10
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _