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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCD2
All Species:
3.64
Human Site:
S549
Identified Species:
8.89
UniProt:
Q9BXW9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXW9
NP_001018125.1
1471
166462
S549
S
K
Q
N
E
A
S
S
H
I
Q
D
D
M
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541774
1447
163939
H549
S
K
H
E
A
S
S
H
I
Q
D
D
M
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80V62
1450
163599
N547
S
Q
Q
P
G
T
S
N
H
I
Q
D
D
M
H
Rat
Rattus norvegicus
Q6IV68
1451
163602
N549
S
Q
Q
P
G
T
S
N
H
I
Q
D
D
M
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001034350
1439
160716
Y552
S
Q
R
Q
E
G
S
Y
I
Q
D
D
M
H
M
Frog
Xenopus laevis
NP_001089160
1443
162550
H551
S
R
G
Q
E
G
G
H
I
Q
D
D
M
F
I
Zebra Danio
Brachydanio rerio
NP_958498
1445
161820
H550
G
Q
E
Q
H
G
G
H
I
Q
D
D
M
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996246
1478
167444
C582
P
D
P
N
L
S
P
C
L
Q
L
Q
E
Q
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002308832
1476
164919
S558
S
S
T
Y
C
F
G
S
S
I
A
D
E
L
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193233
1489
166780
Q585
V
P
D
F
S
S
S
Q
V
S
D
C
G
E
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
83.8
N.A.
72.6
74.3
N.A.
N.A.
55.5
57.2
52.8
N.A.
22.3
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
90.2
N.A.
82.3
83.4
N.A.
N.A.
71.6
72.8
69.8
N.A.
44
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
26.6
N.A.
66.6
66.6
N.A.
N.A.
26.6
20
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
33.3
N.A.
80
80
N.A.
N.A.
40
26.6
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
27.7
N.A.
N.A.
22.7
N.A.
N.A.
Protein Similarity:
48.3
N.A.
N.A.
43.3
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
10
0
0
0
10
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
0
0
50
80
30
0
0
% D
% Glu:
0
0
10
10
30
0
0
0
0
0
0
0
20
10
0
% E
% Phe:
0
0
0
10
0
10
0
0
0
0
0
0
0
10
10
% F
% Gly:
10
0
10
0
20
30
30
0
0
0
0
0
10
0
0
% G
% His:
0
0
10
0
10
0
0
30
30
0
0
0
0
30
30
% H
% Ile:
0
0
0
0
0
0
0
0
40
40
0
0
0
0
30
% I
% Lys:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
10
0
10
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
40
30
10
% M
% Asn:
0
0
0
20
0
0
0
20
0
0
0
0
0
0
0
% N
% Pro:
10
10
10
20
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
40
30
30
0
0
0
10
0
50
30
10
0
10
0
% Q
% Arg:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
70
10
0
0
10
30
60
20
10
10
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
20
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _