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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCD2
All Species:
9.39
Human Site:
S612
Identified Species:
22.96
UniProt:
Q9BXW9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXW9
NP_001018125.1
1471
166462
S612
E
Q
C
T
Q
V
T
S
L
L
Q
L
V
H
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541774
1447
163939
Q612
T
Q
V
T
S
L
L
Q
L
V
H
S
C
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80V62
1450
163599
S610
E
Q
R
T
Q
V
T
S
L
L
Q
L
V
H
S
Rat
Rattus norvegicus
Q6IV68
1451
163602
S612
E
Q
H
T
Q
V
T
S
L
L
Q
L
V
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001034350
1439
160716
L615
C
D
G
Q
L
S
T
L
L
D
L
V
G
F
C
Frog
Xenopus laevis
NP_001089160
1443
162550
L614
F
R
Q
V
T
A
L
L
E
L
L
Q
T
C
S
Zebra Danio
Brachydanio rerio
NP_958498
1445
161820
E613
R
Q
V
M
A
L
L
E
L
V
R
S
C
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996246
1478
167444
G645
N
V
D
S
L
P
D
G
R
G
K
M
A
A
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002308832
1476
164919
S621
A
L
E
L
L
R
T
S
L
D
S
C
K
Q
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193233
1489
166780
D648
F
E
S
L
F
L
A
D
L
E
N
E
K
M
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
83.8
N.A.
72.6
74.3
N.A.
N.A.
55.5
57.2
52.8
N.A.
22.3
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
90.2
N.A.
82.3
83.4
N.A.
N.A.
71.6
72.8
69.8
N.A.
44
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
20
N.A.
93.3
93.3
N.A.
N.A.
13.3
13.3
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
33.3
N.A.
93.3
93.3
N.A.
N.A.
20
20
33.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
27.7
N.A.
N.A.
22.7
N.A.
N.A.
Protein Similarity:
48.3
N.A.
N.A.
43.3
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
10
10
0
0
0
0
0
10
10
10
% A
% Cys:
10
0
10
0
0
0
0
0
0
0
0
10
20
10
10
% C
% Asp:
0
10
10
0
0
0
10
10
0
20
0
0
0
0
0
% D
% Glu:
30
10
10
0
0
0
0
10
10
10
0
10
0
0
20
% E
% Phe:
20
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
10
0
0
0
0
10
0
10
0
0
10
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
10
0
0
30
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
20
0
0
% K
% Leu:
0
10
0
20
30
30
30
20
80
40
20
30
0
0
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
10
0
10
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
50
10
10
30
0
0
10
0
0
30
10
0
10
0
% Q
% Arg:
10
10
10
0
0
10
0
0
10
0
10
0
0
0
0
% R
% Ser:
0
0
10
10
10
10
0
40
0
0
10
20
0
20
40
% S
% Thr:
10
0
0
40
10
0
50
0
0
0
0
0
10
0
0
% T
% Val:
0
10
20
10
0
30
0
0
0
20
0
10
30
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _