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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAK16 All Species: 37.58
Human Site: S232 Identified Species: 63.59
UniProt: Q9BXY0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BXY0 NP_115898.2 300 35369 S232 E V D E S D I S D F E D M D K
Chimpanzee Pan troglodytes XP_001169206 300 35334 S232 E V D E S D I S D F E D M D K
Rhesus Macaque Macaca mulatta XP_001086781 300 35426 S232 E V D E S D I S D F E D M D K
Dog Lupus familis XP_532811 412 47410 S345 E V D E S D I S D F E D M D K
Cat Felis silvestris
Mouse Mus musculus Q8BGS0 296 35167 S231 E V E E S D L S D F E D M D K
Rat Rattus norvegicus NP_001014024 293 34852 S227 E D D E V E E S D L S D F E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505467 298 34960 S233 E M D E S D L S D F E D M D K
Chicken Gallus gallus XP_424533 292 34889 S227 E A D D S D L S D F E D M D K
Frog Xenopus laevis Q66L33 301 35266 S230 N V D E S D L S D F E D M D K
Zebra Danio Brachydanio rerio Q6NYD4 303 35845 S228 E F E E S D L S D F E E L N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572508 343 40567 G266 D D Y D S D S G K R E E V E V
Honey Bee Apis mellifera XP_623781 287 34347 Q222 I E R E V E L Q L E A D E R E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791474 305 35804 E237 E S D L S D F E D M D K L R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P10962 306 35676 A239 D D L E K W L A D S D R E A S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.3 68.9 N.A. 89 87.6 N.A. 79.6 79.6 80 74.2 N.A. 47.8 50 N.A. 60.9
Protein Similarity: 100 99.6 98.6 70.1 N.A. 95 94 N.A. 92 90 88.6 89.1 N.A. 65.3 71.3 N.A. 74.4
P-Site Identity: 100 100 100 100 N.A. 86.6 40 N.A. 86.6 80 86.6 53.3 N.A. 20 13.3 N.A. 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 53.3 N.A. 100 93.3 93.3 86.6 N.A. 53.3 33.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 47.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 67.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 8 0 0 8 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 22 65 15 0 79 0 0 86 0 15 72 0 58 8 % D
% Glu: 72 8 15 79 0 15 8 8 0 8 72 15 15 15 8 % E
% Phe: 0 8 0 0 0 0 8 0 0 65 0 0 8 0 0 % F
% Gly: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 29 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 0 0 8 0 0 8 0 0 58 % K
% Leu: 0 0 8 8 0 0 50 0 8 8 0 0 15 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 8 0 0 58 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 8 0 8 0 15 0 % R
% Ser: 0 8 0 0 79 0 8 72 0 8 8 0 0 0 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 43 0 0 15 0 0 0 0 0 0 0 8 0 8 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _