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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAK16
All Species:
20
Human Site:
S252
Identified Species:
33.85
UniProt:
Q9BXY0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.46
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXY0
NP_115898.2
300
35369
S252
D
E
D
Q
D
G
K
S
S
S
E
E
E
E
E
Chimpanzee
Pan troglodytes
XP_001169206
300
35334
S252
D
E
D
Q
D
G
K
S
S
S
E
E
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001086781
300
35426
S252
D
E
D
Q
D
G
K
S
S
S
E
E
E
E
E
Dog
Lupus familis
XP_532811
412
47410
S365
D
E
D
Q
D
D
K
S
S
S
E
E
E
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS0
296
35167
S251
E
E
D
Q
D
D
E
S
S
N
D
E
E
A
H
Rat
Rattus norvegicus
NP_001014024
293
34852
E247
T
D
S
E
E
D
D
E
S
S
R
E
E
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505467
298
34960
D253
E
E
E
E
E
E
E
D
D
D
G
G
D
Q
K
Chicken
Gallus gallus
XP_424533
292
34889
E247
E
E
E
Q
E
D
E
E
E
T
E
K
K
A
T
Frog
Xenopus laevis
Q66L33
301
35266
E250
D
E
D
K
H
S
S
E
S
E
E
E
S
S
E
Zebra Danio
Brachydanio rerio
Q6NYD4
303
35845
E248
D
E
E
V
N
D
E
E
E
S
S
E
E
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572508
343
40567
A286
E
S
D
E
D
D
D
A
D
A
D
D
I
E
E
Honey Bee
Apis mellifera
XP_623781
287
34347
A242
N
E
P
H
F
V
E
A
E
T
D
E
E
D
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791474
305
35804
D257
S
S
S
D
D
D
E
D
E
S
D
D
E
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10962
306
35676
S259
E
S
D
S
E
S
E
S
D
S
D
S
D
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.3
68.9
N.A.
89
87.6
N.A.
79.6
79.6
80
74.2
N.A.
47.8
50
N.A.
60.9
Protein Similarity:
100
99.6
98.6
70.1
N.A.
95
94
N.A.
92
90
88.6
89.1
N.A.
65.3
71.3
N.A.
74.4
P-Site Identity:
100
100
100
86.6
N.A.
53.3
33.3
N.A.
6.6
20
46.6
40
N.A.
26.6
20
N.A.
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
80
53.3
N.A.
60
66.6
53.3
60
N.A.
66.6
66.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
47.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
15
0
8
0
0
0
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
43
8
58
8
50
50
15
15
22
8
36
15
15
8
8
% D
% Glu:
36
72
22
22
29
8
50
29
29
8
43
65
65
50
58
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
22
0
0
0
0
8
8
0
0
0
% G
% His:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
0
0
29
0
0
0
0
8
8
0
15
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
43
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
8
22
15
8
0
15
8
43
50
58
8
8
8
15
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
15
0
0
0
0
8
% T
% Val:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _