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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAK16 All Species: 21.52
Human Site: S253 Identified Species: 36.41
UniProt: Q9BXY0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.54
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BXY0 NP_115898.2 300 35369 S253 E D Q D G K S S S E E E E E K
Chimpanzee Pan troglodytes XP_001169206 300 35334 S253 E D Q D G K S S S E E E E E K
Rhesus Macaque Macaca mulatta XP_001086781 300 35426 S253 E D Q D G K S S S E E E E E K
Dog Lupus familis XP_532811 412 47410 S366 E D Q D D K S S S E E E E K V
Cat Felis silvestris
Mouse Mus musculus Q8BGS0 296 35167 S252 E D Q D D E S S N D E E A H K
Rat Rattus norvegicus NP_001014024 293 34852 S248 D S E E D D E S S R E E E A H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505467 298 34960 D254 E E E E E E D D D G G D Q K V
Chicken Gallus gallus XP_424533 292 34889 E248 E E Q E D E E E T E K K A T H
Frog Xenopus laevis Q66L33 301 35266 S251 E D K H S S E S E E E S S E E
Zebra Danio Brachydanio rerio Q6NYD4 303 35845 E249 E E V N D E E E S S E E S E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572508 343 40567 D287 S D E D D D A D A D D I E E T
Honey Bee Apis mellifera XP_623781 287 34347 E243 E P H F V E A E T D E E D D D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791474 305 35804 E258 S S D D D E D E S D D E L E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P10962 306 35676 D260 S D S E S E S D S D S D E E N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.3 68.9 N.A. 89 87.6 N.A. 79.6 79.6 80 74.2 N.A. 47.8 50 N.A. 60.9
Protein Similarity: 100 99.6 98.6 70.1 N.A. 95 94 N.A. 92 90 88.6 89.1 N.A. 65.3 71.3 N.A. 74.4
P-Site Identity: 100 100 100 80 N.A. 60 33.3 N.A. 6.6 20 40 33.3 N.A. 26.6 20 N.A. 33.3
P-Site Similarity: 100 100 100 86.6 N.A. 80 53.3 N.A. 53.3 60 53.3 60 N.A. 60 60 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 47.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 67.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 15 0 8 0 0 0 15 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 58 8 50 50 15 15 22 8 36 15 15 8 8 8 % D
% Glu: 72 22 22 29 8 50 29 29 8 43 65 65 50 58 15 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 22 0 0 0 0 8 8 0 0 0 0 % G
% His: 0 0 8 8 0 0 0 0 0 0 0 0 0 8 15 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 8 0 0 29 0 0 0 0 8 8 0 15 36 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 8 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 43 0 0 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 22 15 8 0 15 8 43 50 58 8 8 8 15 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 15 0 0 0 0 8 8 % T
% Val: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _