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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAK16 All Species: 43.64
Human Site: T174 Identified Species: 73.85
UniProt: Q9BXY0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BXY0 NP_115898.2 300 35369 T174 L E R L K Q D T Y G D I Y N F
Chimpanzee Pan troglodytes XP_001169206 300 35334 T174 L E R L K Q D T Y G D I Y N F
Rhesus Macaque Macaca mulatta XP_001086781 300 35426 T174 L E R L K Q D T Y G D I Y N F
Dog Lupus familis XP_532811 412 47410 T290 L E R L K Q D T Y G D I Y N F
Cat Felis silvestris
Mouse Mus musculus Q8BGS0 296 35167 T174 L E R L K Q D T Y G D I Y N F
Rat Rattus norvegicus NP_001014024 293 34852 T174 L E R L K Q D T Y G D I Y N F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505467 298 34960 T174 L Q R L K Q E T Y G D V Y N F
Chicken Gallus gallus XP_424533 292 34889 T174 L E R L K Q D T Y G D I Y N F
Frog Xenopus laevis Q66L33 301 35266 A174 L E R L K Q G A Y G D I Y N F
Zebra Danio Brachydanio rerio Q6NYD4 303 35845 T174 L D R L K Q G T Y G D I Y N F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572508 343 40567 T173 M D R L K N G T Y R D I Y N F
Honey Bee Apis mellifera XP_623781 287 34347 M173 M E R L K Q G M Y N D I Y N F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791474 305 35804 T175 L D R L K S G T Y G D I Y N F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P10962 306 35676 A174 M D R L K S G A Y G D K P L N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.3 68.9 N.A. 89 87.6 N.A. 79.6 79.6 80 74.2 N.A. 47.8 50 N.A. 60.9
Protein Similarity: 100 99.6 98.6 70.1 N.A. 95 94 N.A. 92 90 88.6 89.1 N.A. 65.3 71.3 N.A. 74.4
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 80 100 86.6 86.6 N.A. 66.6 73.3 N.A. 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 86.6 93.3 N.A. 80 80 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 47.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 67.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 40 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 29 0 0 0 0 50 0 0 0 100 0 0 0 0 % D
% Glu: 0 65 0 0 0 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93 % F
% Gly: 0 0 0 0 0 0 43 0 0 86 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 86 0 0 0 % I
% Lys: 0 0 0 0 100 0 0 0 0 0 0 8 0 0 0 % K
% Leu: 79 0 0 100 0 0 0 0 0 0 0 0 0 8 0 % L
% Met: 22 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 8 0 0 0 93 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % P
% Gln: 0 8 0 0 0 79 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 100 0 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 79 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 100 0 0 0 93 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _