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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPA
All Species:
45.45
Human Site:
S176
Identified Species:
83.33
UniProt:
Q9BY32
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BY32
NP_258412.1
194
21446
S176
K
A
E
K
N
A
V
S
H
R
F
R
A
L
L
Chimpanzee
Pan troglodytes
XP_001161047
194
21399
S176
K
A
E
K
N
A
V
S
H
R
F
R
A
L
L
Rhesus Macaque
Macaca mulatta
XP_001115179
208
22573
S176
K
A
E
K
N
A
V
S
H
R
F
R
A
L
L
Dog
Lupus familis
XP_851574
348
37760
S315
K
A
K
K
N
A
I
S
H
R
F
R
A
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D892
198
21879
S176
K
S
E
K
N
T
I
S
H
R
F
R
A
L
H
Rat
Rattus norvegicus
NP_001101244
198
21909
S176
K
A
E
K
N
T
I
S
H
R
F
R
A
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422234
201
22244
S175
K
A
V
K
N
S
I
S
H
R
Y
R
A
L
S
Frog
Xenopus laevis
NP_001089939
195
21785
S175
K
E
V
K
N
T
I
S
H
R
Y
R
A
L
K
Zebra Danio
Brachydanio rerio
NP_001093456
203
22851
S174
K
E
V
K
N
S
I
S
H
R
Y
R
A
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608890
191
21430
S170
K
S
E
K
N
T
I
S
H
R
Y
R
A
L
A
Honey Bee
Apis mellifera
XP_001121959
190
21412
S171
K
E
I
K
N
K
I
S
H
R
S
K
A
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001184472
169
18705
S152
N
E
E
K
N
K
I
S
H
R
G
K
A
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47119
197
22075
S179
K
D
A
K
N
A
I
S
H
R
G
K
A
F
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
90.8
52.2
N.A.
87.3
88.3
N.A.
N.A.
74.1
74.8
69.4
N.A.
64.9
59.7
N.A.
59.2
Protein Similarity:
100
100
92.7
54.3
N.A.
92.4
92.4
N.A.
N.A.
85.5
85.6
80.7
N.A.
79.3
75.2
N.A.
71.6
P-Site Identity:
100
100
100
86.6
N.A.
73.3
80
N.A.
N.A.
66.6
60
60
N.A.
66.6
53.3
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
86.6
73.3
80
N.A.
86.6
66.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
58.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
47
8
0
0
39
0
0
0
0
0
0
100
0
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
31
54
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
47
0
0
8
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
8
% H
% Ile:
0
0
8
0
0
0
77
0
0
0
0
0
0
0
0
% I
% Lys:
93
0
8
100
0
16
0
0
0
0
0
24
0
0
16
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
93
31
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
100
0
77
0
0
0
% R
% Ser:
0
16
0
0
0
16
0
100
0
0
8
0
0
0
8
% S
% Thr:
0
0
0
0
0
31
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
24
0
0
0
24
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _