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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHMP4A All Species: 9.7
Human Site: S193 Identified Species: 16.41
UniProt: Q9BY43 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BY43 NP_054888.2 222 25098 S193 E P S V K L P S V P S T H L P
Chimpanzee Pan troglodytes XP_001169292 265 29795 S236 E P P V K L P S V P S T H L P
Rhesus Macaque Macaca mulatta XP_001105255 224 24948 N193 P E T V P L P N V P S I A L P
Dog Lupus familis XP_537387 265 29129 S235 E P P V E L P S V P S T H L P
Cat Felis silvestris
Mouse Mus musculus Q9D8B3 224 24918 N193 P E T V P L P N V P S V A L P
Rat Rattus norvegicus Q569C1 232 26305 N187 M T S M E L P N V P S S S L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZHP5 227 25137 N195 P E T V P L P N V P S I S I P
Frog Xenopus laevis Q5XGW6 222 24831 N191 P E T V P L P N V P A A S L P
Zebra Danio Brachydanio rerio Q6IQ73 224 25158 G183 K D L L Q I S G P E D V P L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVI9 226 25133 V186 D T S Y L D D V V K A P E A P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_495337 221 24666 A197 T P N I A L P A V P A S R P R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SZE4 219 24314 P183 Q P A T T A P P L P S V P V P
Baker's Yeast Sacchar. cerevisiae P39929 240 26969 K181 N A N Q E T S K I V N N N V N
Red Bread Mold Neurospora crassa Q871Y8 228 24957 S184 K L H E T G G S I P V H D K I
Conservation
Percent
Protein Identity: 100 83.4 62.9 76.5 N.A. 63.3 50 N.A. N.A. 62.5 64.8 62 N.A. 25.6 N.A. 55.8 N.A.
Protein Similarity: 100 83.4 81.2 79.2 N.A. 81.2 72.4 N.A. N.A. 80.6 82.8 78.1 N.A. 49.1 N.A. 74.7 N.A.
P-Site Identity: 100 93.3 53.3 86.6 N.A. 53.3 53.3 N.A. N.A. 46.6 46.6 13.3 N.A. 20 N.A. 33.3 N.A.
P-Site Similarity: 100 93.3 66.6 93.3 N.A. 66.6 80 N.A. N.A. 66.6 66.6 40 N.A. 33.3 N.A. 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 39.6 41.2 36.4
Protein Similarity: N.A. N.A. N.A. 55.4 57 55.2
P-Site Identity: N.A. N.A. N.A. 33.3 0 13.3
P-Site Similarity: N.A. N.A. N.A. 60 40 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 8 8 0 8 0 0 22 8 15 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 8 8 0 0 0 8 0 8 0 0 % D
% Glu: 22 29 0 8 22 0 0 0 0 8 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 8 8 0 0 0 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 8 22 0 0 % H
% Ile: 0 0 0 8 0 8 0 0 15 0 0 15 0 8 8 % I
% Lys: 15 0 0 0 15 0 0 8 0 8 0 0 0 8 0 % K
% Leu: 0 8 8 8 8 65 0 0 8 0 0 0 0 58 0 % L
% Met: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 15 0 0 0 0 36 0 0 8 8 8 0 8 % N
% Pro: 29 36 15 0 29 0 72 8 8 79 0 8 15 8 79 % P
% Gln: 8 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % R
% Ser: 0 0 22 0 0 0 15 29 0 0 58 15 22 0 0 % S
% Thr: 8 15 29 8 15 8 0 0 0 0 0 22 0 0 0 % T
% Val: 0 0 0 50 0 0 0 8 72 8 8 22 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _