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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUSP16 All Species: 15.76
Human Site: S596 Identified Species: 34.67
UniProt: Q9BY84 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BY84 NP_085143.1 665 73102 S596 T C G D Q V Y S V R R R Q K P
Chimpanzee Pan troglodytes XP_520751 665 73101 S596 T C G D Q V Y S V R R R Q K P
Rhesus Macaque Macaca mulatta XP_001084619 665 73124 S596 T C G D Q V Y S V R R R Q K P
Dog Lupus familis XP_543810 663 72657 Y593 P T C S D Q V Y S V R R R Q K
Cat Felis silvestris
Mouse Mus musculus O09112 663 68829 S595 S S S S S S S S S S S S S D L
Rat Rattus norvegicus NP_001100094 661 72804 S592 T C S D Q I Y S V R R R Q K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508628 481 51865 S413 H A F L S S S S S S T T T T S
Chicken Gallus gallus XP_428887 701 77250 A632 T G C E Q S C A V R R R T K Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998405 539 59053 A471 G C A V G L E A V R R R G R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10038 657 70984 S589 A S T S T P A S S T P G T S R
Sea Urchin Strong. purpuratus XP_787378 916 99998 I799 E S S Q S Q K I H Q S P T T A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.9 93 N.A. 44.2 90.5 N.A. 52.9 77.1 N.A. 54.5 N.A. N.A. N.A. 30.5 33.7
Protein Similarity: 100 99.5 99 95.7 N.A. 57.8 94.8 N.A. 60.5 83.4 N.A. 64.5 N.A. N.A. N.A. 46.1 47.6
P-Site Identity: 100 100 100 13.3 N.A. 6.6 86.6 N.A. 6.6 46.6 N.A. 33.3 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 100 100 26.6 N.A. 13.3 93.3 N.A. 6.6 60 N.A. 53.3 N.A. N.A. N.A. 6.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 0 0 10 19 0 0 0 0 0 0 10 % A
% Cys: 0 46 19 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 37 10 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 10 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 28 0 10 0 0 0 0 0 0 10 10 0 0 % G
% His: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 0 46 10 % K
% Leu: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 10 0 0 0 0 10 10 0 0 37 % P
% Gln: 0 0 0 10 46 19 0 0 0 10 0 0 37 10 19 % Q
% Arg: 0 0 0 0 0 0 0 0 0 55 64 64 10 10 10 % R
% Ser: 10 28 28 28 28 28 19 64 37 19 19 10 10 10 10 % S
% Thr: 46 10 10 0 10 0 0 0 0 10 10 10 37 19 0 % T
% Val: 0 0 0 10 0 28 10 0 55 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 37 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _