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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHANK3
All Species:
7.88
Human Site:
S1047
Identified Species:
19.26
UniProt:
Q9BYB0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYB0
NP_001073889
1741
186295
S1047
A
P
G
A
D
L
P
S
L
Q
P
S
R
S
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099714
1248
134508
R607
Y
V
H
P
L
T
G
R
L
L
D
P
S
S
P
Dog
Lupus familis
XP_848271
1541
164748
P900
K
P
L
D
P
S
S
P
L
A
L
A
L
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q4ACU6
1805
192199
S1122
P
P
S
A
D
L
P
S
L
Q
P
S
R
S
I
Rat
Rattus norvegicus
Q9JLU4
1815
193239
S1123
P
P
S
A
D
L
P
S
L
Q
P
S
R
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520873
964
102375
R323
P
H
P
E
R
Q
R
R
A
R
S
M
I
I
L
Chicken
Gallus gallus
XP_426415
1770
194380
R1068
P
S
P
I
P
A
P
R
E
P
E
N
L
F
N
Frog
Xenopus laevis
Q52KW0
1292
141161
V650
S
G
N
Y
M
H
P
V
T
G
K
L
L
D
P
Zebra Danio
Brachydanio rerio
XP_001919745
1631
178132
P984
S
P
L
V
K
Q
G
P
V
E
E
G
A
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610925
1871
198983
D1157
L
K
K
R
T
E
N
D
A
V
T
S
A
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
24.7
73.7
N.A.
91
90.4
N.A.
39.3
46
23.8
58.2
N.A.
22
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
37.7
76.3
N.A.
92.3
91.7
N.A.
44.1
61.2
38.3
67.6
N.A.
36.6
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
13.3
13.3
N.A.
86.6
86.6
N.A.
0
6.6
6.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
13.3
26.6
N.A.
86.6
86.6
N.A.
13.3
13.3
13.3
33.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
30
0
10
0
0
20
10
0
10
20
30
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
30
0
0
10
0
0
10
0
0
10
0
% D
% Glu:
0
0
0
10
0
10
0
0
10
10
20
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
10
10
0
0
0
20
0
0
10
0
10
0
0
0
% G
% His:
0
10
10
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
10
10
40
% I
% Lys:
10
10
10
0
10
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
10
0
20
0
10
30
0
0
50
10
10
10
30
0
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
10
0
0
0
10
0
0
0
0
10
0
0
10
% N
% Pro:
40
50
20
10
20
0
50
20
0
10
30
10
0
0
20
% P
% Gln:
0
0
0
0
0
20
0
0
0
30
0
0
0
0
0
% Q
% Arg:
0
0
0
10
10
0
10
30
0
10
0
0
30
0
0
% R
% Ser:
20
10
20
0
0
10
10
30
0
0
10
40
10
40
0
% S
% Thr:
0
0
0
0
10
10
0
0
10
0
10
0
0
0
0
% T
% Val:
0
10
0
10
0
0
0
10
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _