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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACE2 All Species: 12.63
Human Site: S2 Identified Species: 27.78
UniProt: Q9BYF1 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYF1 NP_068576.1 805 92463 S2 _ _ _ _ _ _ M S S S S W L L L
Chimpanzee Pan troglodytes Q9GLN7 1304 149352 P24 L L L L P P Q P A L A L D P G
Rhesus Macaque Macaca mulatta NP_001129168 805 92460 S2 _ _ _ _ _ _ M S G S S W L L L
Dog Lupus familis XP_853294 651 74712
Cat Felis silvestris
Mouse Mus musculus Q8R0I0 805 92349 S2 _ _ _ _ _ _ M S S S S W L L L
Rat Rattus norvegicus Q5EGZ1 805 92472 S2 _ _ _ _ _ _ M S S S C W L L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515597 806 92845 G2 _ _ _ _ _ _ M G G S L W L V F
Chicken Gallus gallus XP_416822 808 92923 L2 _ _ _ _ _ _ M L L H F W L L C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007298 785 90844 R4 _ _ _ _ M C A R W L L L L A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q10714 615 70896
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782641 657 74057
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.2 94.9 34.1 N.A. 82.1 82.4 N.A. 67.7 65.4 N.A. 56.6 N.A. 28.7 N.A. N.A. 37.1
Protein Similarity: 100 40 97.5 48.8 N.A. 89.5 90 N.A. 80 79.5 N.A. 71 N.A. 45.3 N.A. N.A. 51.4
P-Site Identity: 100 0 88.8 0 N.A. 100 88.8 N.A. 44.4 44.4 N.A. 18.1 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 13.3 88.8 0 N.A. 100 88.8 N.A. 55.5 44.4 N.A. 18.1 N.A. 0 N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 10 0 10 0 0 10 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 10 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 0 10 19 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 10 10 10 0 0 0 10 10 19 19 19 64 46 46 % L
% Met: 0 0 0 0 10 0 55 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 10 0 10 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 37 28 46 28 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 55 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 64 64 64 64 55 55 0 0 0 0 0 0 0 0 0 % _