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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACE2 All Species: 20.61
Human Site: S692 Identified Species: 45.33
UniProt: Q9BYF1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYF1 NP_068576.1 805 92463 S692 V T A P K N V S D I I P R T E
Chimpanzee Pan troglodytes Q9GLN7 1304 149352 S1042 L L S S E G G S D E H D I N F
Rhesus Macaque Macaca mulatta NP_001129168 805 92460 S692 V T A P K N V S D I I P R T E
Dog Lupus familis XP_853294 651 74712 F547 F V S F V L Q F Q F H Q A L C
Cat Felis silvestris
Mouse Mus musculus Q8R0I0 805 92349 S692 V T S P Q N V S D V I P R S E
Rat Rattus norvegicus Q5EGZ1 805 92472 S692 V T S P K N V S D I I P R S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515597 806 92845 S695 K V Q N R R D S I Y V P K D E
Chicken Gallus gallus XP_416822 808 92923 S692 V S M P G N V S D I V P R A D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007298 785 90844 P680 N T D V N F T P E N I H T Y N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q10714 615 70896 F511 Y L R Y L V S F I I Q F Q F Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782641 657 74057 F553 G P L H K C D F Y R S T E A G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.2 94.9 34.1 N.A. 82.1 82.4 N.A. 67.7 65.4 N.A. 56.6 N.A. 28.7 N.A. N.A. 37.1
Protein Similarity: 100 40 97.5 48.8 N.A. 89.5 90 N.A. 80 79.5 N.A. 71 N.A. 45.3 N.A. N.A. 51.4
P-Site Identity: 100 13.3 100 0 N.A. 73.3 86.6 N.A. 20 60 N.A. 13.3 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 33.3 100 6.6 N.A. 100 100 N.A. 40 80 N.A. 20 N.A. 13.3 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 0 0 0 0 0 0 0 0 0 10 19 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 10 0 0 0 19 0 55 0 0 10 0 10 10 % D
% Glu: 0 0 0 0 10 0 0 0 10 10 0 0 10 0 46 % E
% Phe: 10 0 0 10 0 10 0 28 0 10 0 10 0 10 10 % F
% Gly: 10 0 0 0 10 10 10 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 10 0 0 0 0 0 0 19 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 19 46 46 0 10 0 0 % I
% Lys: 10 0 0 0 37 0 0 0 0 0 0 0 10 0 0 % K
% Leu: 10 19 10 0 10 10 0 0 0 0 0 0 0 10 0 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 10 10 46 0 0 0 10 0 0 0 10 10 % N
% Pro: 0 10 0 46 0 0 0 10 0 0 0 55 0 0 0 % P
% Gln: 0 0 10 0 10 0 10 0 10 0 10 10 10 0 0 % Q
% Arg: 0 0 10 0 10 10 0 0 0 10 0 0 46 0 0 % R
% Ser: 0 10 37 10 0 0 10 64 0 0 10 0 0 19 0 % S
% Thr: 0 46 0 0 0 0 10 0 0 0 0 10 10 19 0 % T
% Val: 46 19 0 10 10 10 46 0 0 10 19 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 10 0 0 0 0 10 10 0 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _