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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACE2
All Species:
5.76
Human Site:
S776
Identified Species:
12.67
UniProt:
Q9BYF1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYF1
NP_068576.1
805
92463
S776
K
K
K
N
K
A
R
S
G
E
N
P
Y
A
S
Chimpanzee
Pan troglodytes
Q9GLN7
1304
149352
Q1276
V
A
T
L
G
L
S
Q
R
L
F
S
I
R
H
Rhesus Macaque
Macaca mulatta
NP_001129168
805
92460
S776
K
K
K
N
Q
A
R
S
E
E
N
P
Y
A
S
Dog
Lupus familis
XP_853294
651
74712
N623
S
R
W
L
Q
E
Q
N
K
R
N
G
E
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0I0
805
92349
R776
K
K
K
N
E
T
K
R
E
E
N
P
Y
D
S
Rat
Rattus norvegicus
Q5EGZ1
805
92472
R776
K
K
K
N
E
T
K
R
E
E
N
P
Y
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515597
806
92845
N775
I
R
D
R
R
R
K
N
E
E
G
D
S
S
A
Chicken
Gallus gallus
XP_416822
808
92923
A776
R
K
K
A
R
G
R
A
N
E
A
G
S
N
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007298
785
90844
V757
E
K
I
T
I
W
L
V
V
F
G
V
V
M
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q10714
615
70896
E587
K
A
I
A
E
Y
F
E
P
L
R
V
W
L
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782641
657
74057
T629
V
T
T
Q
E
S
T
T
A
G
G
P
S
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.2
94.9
34.1
N.A.
82.1
82.4
N.A.
67.7
65.4
N.A.
56.6
N.A.
28.7
N.A.
N.A.
37.1
Protein Similarity:
100
40
97.5
48.8
N.A.
89.5
90
N.A.
80
79.5
N.A.
71
N.A.
45.3
N.A.
N.A.
51.4
P-Site Identity:
100
0
86.6
6.6
N.A.
60
60
N.A.
6.6
26.6
N.A.
6.6
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
0
93.3
33.3
N.A.
73.3
73.3
N.A.
46.6
46.6
N.A.
13.3
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
19
0
19
0
10
10
0
10
0
0
28
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
10
0
19
0
% D
% Glu:
10
0
0
0
37
10
0
10
37
55
0
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
10
10
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
10
10
28
19
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
10
0
19
0
10
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
46
55
46
0
10
0
28
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
19
0
10
10
0
0
19
0
0
0
10
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
37
0
0
0
19
10
0
46
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
46
0
0
0
% P
% Gln:
0
0
0
10
19
0
10
10
0
0
0
0
0
0
0
% Q
% Arg:
10
19
0
10
19
10
28
19
10
10
10
0
0
10
0
% R
% Ser:
10
0
0
0
0
10
10
19
0
0
0
10
28
10
37
% S
% Thr:
0
10
19
10
0
19
10
10
0
0
0
0
0
0
0
% T
% Val:
19
0
0
0
0
0
0
10
10
0
0
19
10
10
0
% V
% Trp:
0
0
10
0
0
10
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
37
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _