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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACE2 All Species: 10.91
Human Site: S783 Identified Species: 24
UniProt: Q9BYF1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYF1 NP_068576.1 805 92463 S783 S G E N P Y A S I D I S K G E
Chimpanzee Pan troglodytes Q9GLN7 1304 149352 H1283 Q R L F S I R H R S L H R H S
Rhesus Macaque Macaca mulatta NP_001129168 805 92460 S783 S E E N P Y A S I D I N K G E
Dog Lupus familis XP_853294 651 74712 L630 N K R N G E V L G W P E Y Q W
Cat Felis silvestris
Mouse Mus musculus Q8R0I0 805 92349 S783 R E E N P Y D S M D I G K G E
Rat Rattus norvegicus Q5EGZ1 805 92472 S783 R E E N P Y D S M D I G K G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515597 806 92845 A782 N E E G D S S A E N P Y A I G
Chicken Gallus gallus XP_416822 808 92923 C783 A N E A G S N C E V N P Y D E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007298 785 90844 G764 V V F G V V M G V T V L A G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q10714 615 70896 E594 E P L R V W L E A E N I K N N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782641 657 74057 L636 T A G G P S A L G N A S L W M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.2 94.9 34.1 N.A. 82.1 82.4 N.A. 67.7 65.4 N.A. 56.6 N.A. 28.7 N.A. N.A. 37.1
Protein Similarity: 100 40 97.5 48.8 N.A. 89.5 90 N.A. 80 79.5 N.A. 71 N.A. 45.3 N.A. N.A. 51.4
P-Site Identity: 100 0 86.6 6.6 N.A. 66.6 66.6 N.A. 6.6 13.3 N.A. 6.6 N.A. 6.6 N.A. N.A. 20
P-Site Similarity: 100 13.3 93.3 13.3 N.A. 73.3 73.3 N.A. 33.3 20 N.A. 20 N.A. 20 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 10 0 0 28 10 10 0 10 0 19 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 19 0 0 37 0 0 0 10 0 % D
% Glu: 10 37 55 0 0 10 0 10 19 10 0 10 0 0 46 % E
% Phe: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 28 19 0 0 10 19 0 0 19 0 46 10 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 10 0 10 0 % H
% Ile: 0 0 0 0 0 10 0 0 19 0 37 10 0 10 10 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 46 0 0 % K
% Leu: 0 0 19 0 0 0 10 19 0 0 10 10 10 0 0 % L
% Met: 0 0 0 0 0 0 10 0 19 0 0 0 0 0 10 % M
% Asn: 19 10 0 46 0 0 10 0 0 19 19 10 0 10 10 % N
% Pro: 0 10 0 0 46 0 0 0 0 0 19 10 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 19 10 10 10 0 0 10 0 10 0 0 0 10 0 0 % R
% Ser: 19 0 0 0 10 28 10 37 0 10 0 19 0 0 10 % S
% Thr: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % T
% Val: 10 10 0 0 19 10 10 0 10 10 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 10 0 0 0 10 10 % W
% Tyr: 0 0 0 0 0 37 0 0 0 0 0 10 19 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _