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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKI67IP
All Species:
12.12
Human Site:
S218
Identified Species:
24.24
UniProt:
Q9BYG3
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYG3
NP_115766.3
293
34222
S218
R
K
K
K
K
K
V
S
G
T
L
D
T
P
E
Chimpanzee
Pan troglodytes
XP_515769
261
30438
S186
R
K
K
K
K
K
V
S
G
T
L
D
T
P
E
Rhesus Macaque
Macaca mulatta
XP_001085690
293
34043
L218
R
K
K
K
K
K
V
L
G
T
P
N
V
P
E
Dog
Lupus familis
XP_533319
297
34265
S222
K
K
K
K
K
K
S
S
R
T
T
T
T
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91VE6
317
36247
R241
S
N
N
I
P
K
K
R
K
R
S
R
R
K
K
Rat
Rattus norvegicus
Q5RJM0
271
31333
S197
P
K
P
K
K
E
I
S
S
I
A
N
T
H
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519520
250
28510
S182
T
F
L
E
R
R
K
S
V
A
L
G
M
S
E
Chicken
Gallus gallus
XP_422088
277
31398
K201
P
V
K
R
K
K
V
K
R
S
K
A
K
Q
N
Frog
Xenopus laevis
Q7SYS2
278
32306
K192
A
A
H
R
E
M
R
K
E
L
T
C
D
A
N
Zebra Danio
Brachydanio rerio
Q8JIY8
269
30081
K195
F
A
A
Q
I
P
A
K
K
A
P
S
E
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002316513
217
25279
F149
W
K
G
F
N
Y
R
F
N
P
V
D
R
L
Q
Maize
Zea mays
NP_001148652
215
24686
F147
W
K
G
V
R
R
G
F
I
P
V
D
R
V
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
94.1
73.7
N.A.
56.7
58
N.A.
36.1
50.1
40.6
46
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.7
96.9
84.8
N.A.
71.9
73.7
N.A.
50.5
65.1
55.9
61.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
73.3
66.6
N.A.
6.6
33.3
N.A.
20
26.6
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
73.3
N.A.
13.3
53.3
N.A.
40
40
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
27.6
26.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
46
43.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
9
0
0
0
9
0
0
17
9
9
0
17
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
34
9
0
0
% D
% Glu:
0
0
0
9
9
9
0
0
9
0
0
0
9
0
42
% E
% Phe:
9
9
0
9
0
0
0
17
0
0
0
0
0
0
0
% F
% Gly:
0
0
17
0
0
0
9
0
25
0
0
9
0
0
9
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
9
9
0
9
0
9
9
0
0
0
0
0
% I
% Lys:
9
59
42
42
50
50
17
25
17
0
9
0
9
9
9
% K
% Leu:
0
0
9
0
0
0
0
9
0
9
25
0
0
9
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
9
9
0
9
0
0
0
9
0
0
17
0
0
25
% N
% Pro:
17
0
9
0
9
9
0
0
0
17
17
0
0
34
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
9
% Q
% Arg:
25
0
0
17
17
17
17
9
17
9
0
9
25
0
0
% R
% Ser:
9
0
0
0
0
0
9
42
9
9
9
9
0
9
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
34
17
9
34
0
0
% T
% Val:
0
9
0
9
0
0
34
0
9
0
17
0
9
9
0
% V
% Trp:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _