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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MKI67IP All Species: 16.67
Human Site: T279 Identified Species: 33.33
UniProt: Q9BYG3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYG3 NP_115766.3 293 34222 T279 E E I Q E T Q T P T H S R K K
Chimpanzee Pan troglodytes XP_515769 261 30438 T247 E E I Q E T Q T P T H S R K K
Rhesus Macaque Macaca mulatta XP_001085690 293 34043 T279 E E I Q E T Q T P T H S R K K
Dog Lupus familis XP_533319 297 34265 T283 E E T Q E T Q T P T R S R K K
Cat Felis silvestris
Mouse Mus musculus Q91VE6 317 36247 T301 E D T Q K T P T S A S P G G K
Rat Rattus norvegicus Q5RJM0 271 31333 A255 E D T Q K T P A P E S S G K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519520 250 28510 D237 S Q F S Q N L D T T D E S S G
Chicken Gallus gallus XP_422088 277 31398 K260 K A V Q R P K K Q P R K K K Q
Frog Xenopus laevis Q7SYS2 278 32306 K255 V V V K L P Q K V S S A A K R
Zebra Danio Brachydanio rerio Q8JIY8 269 30081 E255 D D V E E S E E E S A E E D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002316513 217 25279 D204 E C P E F V G D V K C V P K K
Maize Zea mays NP_001148652 215 24686 S202 E C P A L I G S I Q P S A K K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88 94.1 73.7 N.A. 56.7 58 N.A. 36.1 50.1 40.6 46 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.7 96.9 84.8 N.A. 71.9 73.7 N.A. 50.5 65.1 55.9 61.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 33.3 46.6 N.A. 6.6 13.3 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 46.6 60 N.A. 20 46.6 46.6 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 27.6 26.6 N.A. N.A. N.A. N.A.
Protein Similarity: 46 43.3 N.A. N.A. N.A. N.A.
P-Site Identity: 20 26.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 26.6 33.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 0 0 9 0 9 9 9 17 0 0 % A
% Cys: 0 17 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 9 25 0 0 0 0 0 17 0 0 9 0 0 9 0 % D
% Glu: 67 34 0 17 42 0 9 9 9 9 0 17 9 0 9 % E
% Phe: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 17 0 0 0 0 0 17 9 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 % H
% Ile: 0 0 25 0 0 9 0 0 9 0 0 0 0 0 0 % I
% Lys: 9 0 0 9 17 0 9 17 0 9 0 9 9 75 67 % K
% Leu: 0 0 0 0 17 0 9 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 17 0 0 17 17 0 42 9 9 9 9 0 0 % P
% Gln: 0 9 0 59 9 0 42 0 9 9 0 0 0 0 9 % Q
% Arg: 0 0 0 0 9 0 0 0 0 0 17 0 34 0 9 % R
% Ser: 9 0 0 9 0 9 0 9 9 17 25 50 9 9 0 % S
% Thr: 0 0 25 0 0 50 0 42 9 42 0 0 0 0 0 % T
% Val: 9 9 25 0 0 9 0 0 17 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _