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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MKI67IP All Species: 17.27
Human Site: T72 Identified Species: 34.55
UniProt: Q9BYG3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYG3 NP_115766.3 293 34222 T72 F S Q F G T V T R F R L S R S
Chimpanzee Pan troglodytes XP_515769 261 30438 K68 F E S K D V A K I V A E T M N
Rhesus Macaque Macaca mulatta XP_001085690 293 34043 T72 F S Q F G T V T R F R L S R S
Dog Lupus familis XP_533319 297 34265 T72 F S Q F G T V T R F R L S R S
Cat Felis silvestris
Mouse Mus musculus Q91VE6 317 36247 S74 C A Q F G D I S R F R L S R S
Rat Rattus norvegicus Q5RJM0 271 31333 R71 C A Q F G D I R R F R L S R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519520 250 28510 N66 Q I V A E T M N N Y L F C E R
Chicken Gallus gallus XP_422088 277 31398 R72 F E Q F G T V R R L R L S R S
Frog Xenopus laevis Q7SYS2 278 32306 T68 F N Q F G T V T R L R L S R S
Zebra Danio Brachydanio rerio Q8JIY8 269 30081 L72 F E Q F G K V L R L R V S R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002316513 217 25279 D33 N G K Q A A A D F L P L E G G
Maize Zea mays NP_001148652 215 24686 P31 G E G K D F L P L E G G P G K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88 94.1 73.7 N.A. 56.7 58 N.A. 36.1 50.1 40.6 46 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.7 96.9 84.8 N.A. 71.9 73.7 N.A. 50.5 65.1 55.9 61.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 100 N.A. 66.6 66.6 N.A. 6.6 80 86.6 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 100 N.A. 86.6 80 N.A. 20 80 93.3 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 27.6 26.6 N.A. N.A. N.A. N.A.
Protein Similarity: 46 43.3 N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 6.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 9 9 9 17 0 0 0 9 0 0 0 0 % A
% Cys: 17 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 0 0 17 17 0 9 0 0 0 0 0 0 0 % D
% Glu: 0 34 0 0 9 0 0 0 0 9 0 9 9 9 0 % E
% Phe: 59 0 0 67 0 9 0 0 9 42 0 9 0 0 0 % F
% Gly: 9 9 9 0 67 0 0 0 0 0 9 9 0 17 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 17 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 9 17 0 9 0 9 0 0 0 0 0 0 9 % K
% Leu: 0 0 0 0 0 0 9 9 9 34 9 67 0 0 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % M
% Asn: 9 9 0 0 0 0 0 9 9 0 0 0 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 9 0 0 9 0 9 0 0 % P
% Gln: 9 0 67 9 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 17 67 0 67 0 0 67 9 % R
% Ser: 0 25 9 0 0 0 0 9 0 0 0 0 67 0 67 % S
% Thr: 0 0 0 0 0 50 0 34 0 0 0 0 9 0 0 % T
% Val: 0 0 9 0 0 9 50 0 0 9 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _