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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GSDMC
All Species:
5.15
Human Site:
S48
Identified Species:
18.89
UniProt:
Q9BYG8
Number Species:
6
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYG8
NP_113603.1
508
57662
S48
K
K
K
D
S
R
S
S
F
W
E
Q
S
D
Y
Chimpanzee
Pan troglodytes
XP_001153860
508
57633
S48
K
K
K
D
S
R
S
S
F
W
E
Q
S
D
Y
Rhesus Macaque
Macaca mulatta
XP_001083863
507
57388
I48
K
K
D
S
R
S
S
I
W
G
Q
S
D
Y
V
Dog
Lupus familis
XP_852261
996
109822
D63
S
K
H
H
E
G
L
D
L
F
C
S
T
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99NB5
468
52725
S43
F
N
I
L
Q
E
T
S
S
R
L
A
L
K
T
Rat
Rattus norvegicus
P85967
474
53233
F48
K
T
P
Q
S
L
F
F
K
S
E
D
T
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505287
446
48775
D21
R
Q
L
N
P
Q
G
D
L
T
P
L
D
S
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
92.1
25.7
N.A.
45.2
47.8
N.A.
31.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
95.2
36.2
N.A.
62.5
63.5
N.A.
47.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
6.6
N.A.
6.6
20
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
20
N.A.
13.3
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% C
% Asp:
0
0
15
29
0
0
0
29
0
0
0
15
29
29
0
% D
% Glu:
0
0
0
0
15
15
0
0
0
0
43
0
0
0
0
% E
% Phe:
15
0
0
0
0
0
15
15
29
15
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
15
15
0
0
15
0
0
0
0
0
% G
% His:
0
0
15
15
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
0
0
0
15
0
0
0
0
0
15
0
% I
% Lys:
58
58
29
0
0
0
0
0
15
0
0
0
0
15
0
% K
% Leu:
0
0
15
15
0
15
15
0
29
0
15
15
15
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
15
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
15
0
15
0
0
0
0
0
15
0
0
15
0
% P
% Gln:
0
15
0
15
15
15
0
0
0
0
15
29
0
0
0
% Q
% Arg:
15
0
0
0
15
29
0
0
0
15
0
0
0
0
0
% R
% Ser:
15
0
0
15
43
15
43
43
15
15
0
29
29
15
0
% S
% Thr:
0
15
0
0
0
0
15
0
0
15
0
0
29
0
29
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% V
% Trp:
0
0
0
0
0
0
0
0
15
29
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
29
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _