KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEZ6L
All Species:
5.76
Human Site:
S678
Identified Species:
21.11
UniProt:
Q9BYH1
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYH1
NP_066938.2
1024
111782
S678
Q
F
L
N
L
S
N
S
D
I
L
T
I
Y
D
Chimpanzee
Pan troglodytes
XP_515042
1117
120856
R673
L
L
L
H
D
K
D
R
M
T
V
H
S
G
Q
Rhesus Macaque
Macaca mulatta
XP_001104921
783
86799
Y443
N
S
D
I
L
T
I
Y
D
G
D
E
V
M
P
Dog
Lupus familis
XP_543455
1015
110779
S669
Q
F
L
N
L
S
N
S
D
I
L
T
I
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1D5
963
104808
I623
S
N
S
D
I
L
T
I
Y
D
G
D
E
V
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415197
951
103889
R611
D
G
D
E
L
S
A
R
I
L
G
Q
Y
V
G
Frog
Xenopus laevis
Q6AX42
900
98375
G560
D
A
L
T
V
Y
D
G
D
D
L
T
A
R
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.3
75.2
89.2
N.A.
81
N.A.
N.A.
N.A.
71.9
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
84.5
76
90.8
N.A.
86.7
N.A.
N.A.
N.A.
80.1
61.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
13.3
100
N.A.
0
N.A.
N.A.
N.A.
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
26.6
100
N.A.
13.3
N.A.
N.A.
N.A.
20
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
15
0
0
0
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
0
29
15
15
0
29
0
58
29
15
15
0
0
29
% D
% Glu:
0
0
0
15
0
0
0
0
0
0
0
15
15
0
0
% E
% Phe:
0
29
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
15
0
0
0
0
0
15
0
15
29
0
0
15
15
% G
% His:
0
0
0
15
0
0
0
0
0
0
0
15
0
0
0
% H
% Ile:
0
0
0
15
15
0
15
15
15
29
0
0
29
0
0
% I
% Lys:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% K
% Leu:
15
15
58
0
58
15
0
0
0
15
43
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
15
0
0
0
0
15
0
% M
% Asn:
15
15
0
29
0
0
29
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% P
% Gln:
29
0
0
0
0
0
0
0
0
0
0
15
0
0
15
% Q
% Arg:
0
0
0
0
0
0
0
29
0
0
0
0
0
15
0
% R
% Ser:
15
15
15
0
0
43
0
29
0
0
0
0
15
0
0
% S
% Thr:
0
0
0
15
0
15
15
0
0
15
0
43
0
0
0
% T
% Val:
0
0
0
0
15
0
0
0
0
0
15
0
15
29
29
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
15
0
15
15
0
0
0
15
29
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _