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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEZ6L All Species: 6.36
Human Site: S782 Identified Species: 23.33
UniProt: Q9BYH1 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYH1 NP_066938.2 1024 111782 S782 P G Y D I V G S D T L T C Q W
Chimpanzee Pan troglodytes XP_515042 1117 120856 C822 P Y V E G E D C I W K I H V G
Rhesus Macaque Macaca mulatta XP_001104921 783 86799 T545 I V G S D T L T C Q W D L S W
Dog Lupus familis XP_543455 1015 110779 S773 P G Y D I V G S D T L T C Q W
Cat Felis silvestris
Mouse Mus musculus Q6P1D5 963 104808 L725 D I V G S D T L T C Q W D L S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415197 951 103889 S713 C Q W D L S W S S D P P F C E
Frog Xenopus laevis Q6AX42 900 98375 Q662 G S D I L T C Q W D L S W S N
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.3 75.2 89.2 N.A. 81 N.A. N.A. N.A. 71.9 45.2 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 84.5 76 90.8 N.A. 86.7 N.A. N.A. N.A. 80.1 61.9 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 100 N.A. 0 N.A. N.A. N.A. 13.3 6.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 13.3 100 N.A. 0 N.A. N.A. N.A. 26.6 20 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 15 0 0 0 0 0 15 15 15 15 0 0 29 15 0 % C
% Asp: 15 0 15 43 15 15 15 0 29 29 0 15 15 0 0 % D
% Glu: 0 0 0 15 0 15 0 0 0 0 0 0 0 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % F
% Gly: 15 29 15 15 15 0 29 0 0 0 0 0 0 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % H
% Ile: 15 15 0 15 29 0 0 0 15 0 0 15 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % K
% Leu: 0 0 0 0 29 0 15 15 0 0 43 0 15 15 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % N
% Pro: 43 0 0 0 0 0 0 0 0 0 15 15 0 0 0 % P
% Gln: 0 15 0 0 0 0 0 15 0 15 15 0 0 29 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 15 0 15 15 15 0 43 15 0 0 15 0 29 15 % S
% Thr: 0 0 0 0 0 29 15 15 15 29 0 29 0 0 0 % T
% Val: 0 15 29 0 0 29 0 0 0 0 0 0 0 15 0 % V
% Trp: 0 0 15 0 0 0 15 0 15 15 15 15 15 0 43 % W
% Tyr: 0 15 29 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _