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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM126A
All Species:
27.88
Human Site:
S495
Identified Species:
61.33
UniProt:
Q9BYI3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYI3
NP_115970.2
521
57625
S495
E
E
K
L
I
Y
V
S
E
R
T
E
L
P
M
Chimpanzee
Pan troglodytes
XP_527685
596
65124
S570
E
E
K
L
I
Y
V
S
E
R
T
E
L
P
M
Rhesus Macaque
Macaca mulatta
XP_001101787
521
57616
S495
E
E
K
L
I
Y
V
S
E
R
T
E
L
P
M
Dog
Lupus familis
XP_532489
521
57515
S495
E
E
K
L
I
Y
V
S
E
R
T
E
L
P
M
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9N1
521
57289
S495
E
E
K
L
I
Y
V
S
E
R
T
E
L
A
V
Rat
Rattus norvegicus
XP_575330
521
57136
S495
E
E
K
L
I
Y
G
S
E
R
I
D
L
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513800
607
67012
T582
L
M
Y
I
S
E
R
T
E
L
P
G
P
N
K
Chicken
Gallus gallus
Q5ZM13
515
57202
R490
K
L
I
Y
G
T
E
R
T
D
L
P
V
L
S
Frog
Xenopus laevis
NP_001084860
462
50759
S437
E
E
K
L
M
Y
I
S
K
R
T
E
L
S
V
Zebra Danio
Brachydanio rerio
Q6P121
518
56409
Y493
E
Q
D
E
G
V
A
Y
L
D
H
I
S
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624097
512
56909
N487
T
L
S
G
D
L
D
N
M
E
N
S
I
T
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.7
99.2
97.1
N.A.
91.9
91.1
N.A.
72.4
81
63.9
63.1
N.A.
N.A.
31.2
N.A.
N.A.
Protein Similarity:
100
83.2
99.4
98
N.A.
96.1
95.1
N.A.
77.9
89.6
76.3
76.9
N.A.
N.A.
49.9
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
73.3
N.A.
6.6
0
66.6
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
20
13.3
93.3
20
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
10
0
0
19
0
10
0
0
0
% D
% Glu:
73
64
0
10
0
10
10
0
64
10
0
55
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
19
0
10
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
10
10
55
0
10
0
0
0
10
10
10
0
0
% I
% Lys:
10
0
64
0
0
0
0
0
10
0
0
0
0
0
10
% K
% Leu:
10
19
0
64
0
10
0
0
10
10
10
0
64
10
19
% L
% Met:
0
10
0
0
10
0
0
0
10
0
0
0
0
0
37
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
10
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
10
10
55
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
10
0
64
0
0
0
0
0
% R
% Ser:
0
0
10
0
10
0
0
64
0
0
0
10
10
10
10
% S
% Thr:
10
0
0
0
0
10
0
10
10
0
55
0
0
10
0
% T
% Val:
0
0
0
0
0
10
46
0
0
0
0
0
10
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
0
64
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _