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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNK3
All Species:
26.36
Human Site:
S395
Identified Species:
72.5
UniProt:
Q9BYP7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYP7
NP_001002838.1
1743
191789
S395
Q
N
K
S
E
R
L
S
I
R
D
L
L
N
H
Chimpanzee
Pan troglodytes
XP_001146822
1743
191723
S395
Q
N
K
S
E
R
L
S
I
R
D
L
L
N
H
Rhesus Macaque
Macaca mulatta
XP_001089789
1740
191296
S395
Q
N
K
S
E
R
L
S
I
R
D
L
L
N
H
Dog
Lupus familis
XP_864627
1748
191910
S395
Q
N
K
S
E
R
L
S
I
R
D
L
L
N
H
Cat
Felis silvestris
Mouse
Mus musculus
Q80XP9
1789
197527
S394
Q
N
K
S
E
R
L
S
I
K
D
L
L
N
H
Rat
Rattus norvegicus
Q9JIH7
2126
225198
S469
Q
N
K
D
E
R
Y
S
I
K
D
L
L
N
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508024
2425
260713
E550
K
N
K
E
E
R
Y
E
I
K
D
L
L
S
H
Chicken
Gallus gallus
XP_001235131
2380
248875
A474
Q
N
K
G
E
R
Y
A
I
K
D
L
L
N
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921648
2977
327983
S449
Q
N
R
L
E
R
L
S
V
K
D
L
L
N
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.8
86.6
N.A.
78.4
33.6
N.A.
32.1
31.2
N.A.
30.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.3
91.1
N.A.
84.9
48
N.A.
44.7
44.3
N.A.
40.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
80
N.A.
60
73.3
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
80
86.6
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
0
0
100
0
0
0
0
% D
% Glu:
0
0
0
12
100
0
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% H
% Ile:
0
0
0
0
0
0
0
0
89
0
0
0
0
0
0
% I
% Lys:
12
0
89
0
0
0
0
0
0
56
0
0
0
0
0
% K
% Leu:
0
0
0
12
0
0
67
0
0
0
0
100
100
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
100
0
0
0
0
0
0
0
0
0
0
0
89
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
89
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
12
0
0
100
0
0
0
45
0
0
0
0
0
% R
% Ser:
0
0
0
56
0
0
0
78
0
0
0
0
0
12
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _