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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WNK3 All Species: 23.03
Human Site: T1636 Identified Species: 63.33
UniProt: Q9BYP7 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYP7 NP_001002838.1 1743 191789 T1636 W N K V S E N T P S T M G Y T
Chimpanzee Pan troglodytes XP_001146822 1743 191723 T1636 W N K V S E N T P S T M G Y T
Rhesus Macaque Macaca mulatta XP_001089789 1740 191296 T1634 W N K V Y E N T P S T M G Y T
Dog Lupus familis XP_864627 1748 191910 T1641 W N K V Y E N T P S T M G Y T
Cat Felis silvestris
Mouse Mus musculus Q80XP9 1789 197527 T1682 W N K S C E S T P S T M G Y T
Rat Rattus norvegicus Q9JIH7 2126 225198 T1960 L S A P G Q G T S S T N T V G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508024 2425 260713 Q2310 K A T L T Q T Q N E P C Q V K
Chicken Gallus gallus XP_001235131 2380 248875 T2215 L S A P G Q G T S S T N A V G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921648 2977 327983 T2851 W S Q P A E T T A S S G W F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97.8 86.6 N.A. 78.4 33.6 N.A. 32.1 31.2 N.A. 30.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 98.3 91.1 N.A. 84.9 48 N.A. 44.7 44.3 N.A. 40.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 80 20 N.A. 0 20 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 33.3 N.A. 20 33.3 N.A. 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 23 0 12 0 0 0 12 0 0 0 12 0 0 % A
% Cys: 0 0 0 0 12 0 0 0 0 0 0 12 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 67 0 0 0 12 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % F
% Gly: 0 0 0 0 23 0 23 0 0 0 0 12 56 0 23 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 0 56 0 0 0 0 0 0 0 0 0 0 0 12 % K
% Leu: 23 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 56 0 0 0 % M
% Asn: 0 56 0 0 0 0 45 0 12 0 0 23 0 0 0 % N
% Pro: 0 0 0 34 0 0 0 0 56 0 12 0 0 0 0 % P
% Gln: 0 0 12 0 0 34 0 12 0 0 0 0 12 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 34 0 12 23 0 12 0 23 89 12 0 0 0 12 % S
% Thr: 0 0 12 0 12 0 23 89 0 0 78 0 12 0 56 % T
% Val: 0 0 0 45 0 0 0 0 0 0 0 0 0 34 0 % V
% Trp: 67 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % W
% Tyr: 0 0 0 0 23 0 0 0 0 0 0 0 0 56 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _