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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANO3 All Species: 15.76
Human Site: S450 Identified Species: 34.67
UniProt: Q9BYT9 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYT9 NP_113606.2 981 114655 S450 P L C D K N C S L Q R L N D S
Chimpanzee Pan troglodytes XP_001134642 835 98266 W355 R S I L T Y T W D L I E W E E
Rhesus Macaque Macaca mulatta XP_001091004 981 114692 S450 P L C D K N C S L Q R L N D S
Dog Lupus familis XP_534094 994 115189 G454 V T Y L F D N G G T V F F A I
Cat Felis silvestris
Mouse Mus musculus A2AHL1 981 114549 S450 P L C D K N C S L Q R L N D S
Rat Rattus norvegicus Q6IFT6 860 97152 L380 A L W A V L L L E Y W K R K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509105 975 114441 K443 E R N C T L Q K L N E S C I Y
Chicken Gallus gallus XP_428890 1020 119592 T485 P M C E R N C T L Q K L N E S
Frog Xenopus laevis NP_001086810 896 105149 T416 P E Y E A K C T D K K K N P V
Zebra Danio Brachydanio rerio Q4V8U5 646 74505 V166 R R L Q S K G V L V Q Y F P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001073009 921 106692 A441 N I R P E F E A K A P D R R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.1 99.8 88.2 N.A. 93.6 34.9 N.A. 75.7 73.5 41.2 22.6 N.A. N.A. N.A. N.A. 42.1
Protein Similarity: 100 85.1 99.8 91 N.A. 96.8 55.2 N.A. 86.5 84.4 57.7 38.7 N.A. N.A. N.A. N.A. 57.3
P-Site Identity: 100 0 100 0 N.A. 100 6.6 N.A. 6.6 60 20 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 6.6 100 6.6 N.A. 100 13.3 N.A. 6.6 100 46.6 13.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 10 0 0 10 0 10 0 0 0 10 0 % A
% Cys: 0 0 37 10 0 0 46 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 28 0 10 0 0 19 0 0 10 0 28 0 % D
% Glu: 10 10 0 19 10 0 10 0 10 0 10 10 0 19 10 % E
% Phe: 0 0 0 0 10 10 0 0 0 0 0 10 19 0 0 % F
% Gly: 0 0 0 0 0 0 10 10 10 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 10 0 0 0 0 0 0 0 10 0 0 10 10 % I
% Lys: 0 0 0 0 28 19 0 10 10 10 19 19 0 10 0 % K
% Leu: 0 37 10 19 0 19 10 10 55 10 0 37 0 0 10 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 10 0 0 37 10 0 0 10 0 0 46 0 10 % N
% Pro: 46 0 0 10 0 0 0 0 0 0 10 0 0 19 0 % P
% Gln: 0 0 0 10 0 0 10 0 0 37 10 0 0 0 0 % Q
% Arg: 19 19 10 0 10 0 0 0 0 0 28 0 19 10 0 % R
% Ser: 0 10 0 0 10 0 0 28 0 0 0 10 0 0 37 % S
% Thr: 0 10 0 0 19 0 10 19 0 10 0 0 0 0 0 % T
% Val: 10 0 0 0 10 0 0 10 0 10 10 0 0 0 19 % V
% Trp: 0 0 10 0 0 0 0 10 0 0 10 0 10 0 0 % W
% Tyr: 0 0 19 0 0 10 0 0 0 10 0 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _