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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANO3
All Species:
13.33
Human Site:
T280
Identified Species:
29.33
UniProt:
Q9BYT9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYT9
NP_113606.2
981
114655
T280
L
E
E
S
D
C
Y
T
G
P
F
S
R
A
R
Chimpanzee
Pan troglodytes
XP_001134642
835
98266
N186
V
G
I
R
K
L
I
N
N
G
S
Y
I
A
A
Rhesus Macaque
Macaca mulatta
XP_001091004
981
114692
T280
L
E
E
S
D
C
Y
T
G
P
F
S
R
A
R
Dog
Lupus familis
XP_534094
994
115189
F284
I
N
N
K
D
T
F
F
S
N
A
T
R
S
R
Cat
Felis silvestris
Mouse
Mus musculus
A2AHL1
981
114549
T280
L
E
E
S
D
C
Y
T
G
P
F
S
R
A
R
Rat
Rattus norvegicus
Q6IFT6
860
97152
G211
I
L
A
K
T
P
Y
G
H
Q
K
K
G
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509105
975
114441
F273
T
D
C
Y
T
A
P
F
S
R
A
R
M
H
H
Chicken
Gallus gallus
XP_428890
1020
119592
T315
L
E
E
T
D
C
Y
T
A
P
F
S
R
A
R
Frog
Xenopus laevis
NP_001086810
896
105149
R247
Y
W
K
K
T
D
E
R
S
C
E
R
Y
T
L
Zebra Danio
Brachydanio rerio
Q4V8U5
646
74505
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001073009
921
106692
K272
H
E
G
D
Y
K
S
K
H
S
L
L
T
H
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
99.8
88.2
N.A.
93.6
34.9
N.A.
75.7
73.5
41.2
22.6
N.A.
N.A.
N.A.
N.A.
42.1
Protein Similarity:
100
85.1
99.8
91
N.A.
96.8
55.2
N.A.
86.5
84.4
57.7
38.7
N.A.
N.A.
N.A.
N.A.
57.3
P-Site Identity:
100
6.6
100
20
N.A.
100
6.6
N.A.
0
86.6
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
100
46.6
N.A.
100
13.3
N.A.
6.6
93.3
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
0
0
10
0
19
0
0
46
10
% A
% Cys:
0
0
10
0
0
37
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
10
0
10
46
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
46
37
0
0
0
10
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
19
0
0
37
0
0
0
10
% F
% Gly:
0
10
10
0
0
0
0
10
28
10
0
0
10
0
10
% G
% His:
10
0
0
0
0
0
0
0
19
0
0
0
0
19
10
% H
% Ile:
19
0
10
0
0
0
10
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
10
28
10
10
0
10
0
0
10
10
0
0
0
% K
% Leu:
37
10
0
0
0
10
0
0
0
0
10
10
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
10
0
0
0
0
10
10
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
10
0
0
37
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
10
0
10
0
19
46
0
46
% R
% Ser:
0
0
0
28
0
0
10
0
28
10
10
37
0
10
0
% S
% Thr:
10
0
0
10
28
10
0
37
0
0
0
10
10
10
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
10
0
46
0
0
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _