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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANO3 All Species: 10
Human Site: Y149 Identified Species: 22
UniProt: Q9BYT9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYT9 NP_113606.2 981 114655 Y149 L S K N D M N Y I A S S G P L
Chimpanzee Pan troglodytes XP_001134642 835 98266 K63 S P D I M F I K I H I P W D T
Rhesus Macaque Macaca mulatta XP_001091004 981 114692 Y149 L S K N D M N Y I A S S G P L
Dog Lupus familis XP_534094 994 115189 L152 K K R I D Y I L V Y R K S N I
Cat Felis silvestris
Mouse Mus musculus A2AHL1 981 114549 Y149 L S K N D M S Y I A S S G L L
Rat Rattus norvegicus Q6IFT6 860 97152 E88 I W R E T F L E N L R V A G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509105 975 114441 G150 S G L F F K D G K K R I D Y I
Chicken Gallus gallus XP_428890 1020 119592 A184 S S L K D T D A M A S S G L F
Frog Xenopus laevis NP_001086810 896 105149 T124 H A P W E V L T T Y A E V L N
Zebra Danio Brachydanio rerio Q4V8U5 646 74505
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001073009 921 106692 D149 V K V H A P W D L M T R Y A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.1 99.8 88.2 N.A. 93.6 34.9 N.A. 75.7 73.5 41.2 22.6 N.A. N.A. N.A. N.A. 42.1
Protein Similarity: 100 85.1 99.8 91 N.A. 96.8 55.2 N.A. 86.5 84.4 57.7 38.7 N.A. N.A. N.A. N.A. 57.3
P-Site Identity: 100 6.6 100 6.6 N.A. 86.6 6.6 N.A. 0 40 0 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 6.6 100 26.6 N.A. 93.3 20 N.A. 13.3 53.3 26.6 0 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 0 0 10 0 37 10 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 46 0 19 10 0 0 0 0 10 10 0 % D
% Glu: 0 0 0 10 10 0 0 10 0 0 0 10 0 0 10 % E
% Phe: 0 0 0 10 10 19 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 10 0 0 0 0 0 10 0 0 0 0 37 10 0 % G
% His: 10 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 10 0 0 19 0 0 19 0 37 0 10 10 0 0 19 % I
% Lys: 10 19 28 10 0 10 0 10 10 10 0 10 0 0 0 % K
% Leu: 28 0 19 0 0 0 19 10 10 10 0 0 0 28 37 % L
% Met: 0 0 0 0 10 28 0 0 10 10 0 0 0 0 0 % M
% Asn: 0 0 0 28 0 0 19 0 10 0 0 0 0 10 10 % N
% Pro: 0 10 10 0 0 10 0 0 0 0 0 10 0 19 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 19 0 0 0 0 0 0 0 28 10 0 0 0 % R
% Ser: 28 37 0 0 0 0 10 0 0 0 37 37 10 0 0 % S
% Thr: 0 0 0 0 10 10 0 10 10 0 10 0 0 0 10 % T
% Val: 10 0 10 0 0 10 0 0 10 0 0 10 10 0 0 % V
% Trp: 0 10 0 10 0 0 10 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 10 0 28 0 19 0 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _