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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGXT2 All Species: 5.15
Human Site: S41 Identified Species: 8.72
UniProt: Q9BYV1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYV1 NP_114106.1 514 57156 S41 R T S V T K L S L H T K P R M
Chimpanzee Pan troglodytes XP_526951 513 57215 L41 T S V T K L S L H T K P R M P
Rhesus Macaque Macaca mulatta XP_001090812 514 57272 S41 W T S V T K L S L H T R P R M
Dog Lupus familis XP_855415 520 57365 G47 W T S V T K L G L H T K P R M
Cat Felis silvestris
Mouse Mus musculus Q3UEG6 513 57096 L41 I A V P K L T L H T K H S M P
Rat Rattus norvegicus Q64565 512 57182 H41 Y V P K L T L H T K H N M P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509172 497 55013 S41 C L G G V K S S Y P Y A H I L
Chicken Gallus gallus XP_429219 467 51928 H42 Y K K P L L L H Q G H M Q W L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7SY54 492 54717 E45 K G Q Y M Y N E K D E K Y L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VU95 494 54265 P41 Q L F Y R S D P L K I V R G Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91408 467 51626 K41 R K D T I G S K C Q I F Y S D
Sea Urchin Strong. purpuratus XP_001186664 454 50395 E41 M Q W L W D V E G K R Y L D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q940M2 476 51934 V45 P P H I P P F V H Q P R P Y K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9P3I3 461 49389 Q41 R S Y A T A S Q L T H P D P T
Conservation
Percent
Protein Identity: 100 98.8 96.6 81.7 N.A. 84.8 83 N.A. 67.1 64 N.A. 34 N.A. 35.9 N.A. 31.9 54
Protein Similarity: 100 99 98.2 88.6 N.A. 91.6 89.6 N.A. 80.7 76.6 N.A. 51.9 N.A. 53.3 N.A. 50 67.1
P-Site Identity: 100 0 86.6 86.6 N.A. 0 6.6 N.A. 13.3 6.6 N.A. 6.6 N.A. 6.6 N.A. 6.6 0
P-Site Similarity: 100 6.6 93.3 86.6 N.A. 0 6.6 N.A. 20 13.3 N.A. 13.3 N.A. 13.3 N.A. 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. 44.5 N.A. 27.6
Protein Similarity: N.A. N.A. N.A. 60.7 N.A. 45.5
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 20
P-Site Similarity: N.A. N.A. N.A. 20 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 8 0 0 0 0 0 8 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 8 8 0 0 8 0 0 8 8 15 % D
% Glu: 0 0 0 0 0 0 0 15 0 0 8 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 8 0 0 0 0 8 0 0 0 % F
% Gly: 0 8 8 8 0 8 0 8 8 8 0 0 0 8 0 % G
% His: 0 0 8 0 0 0 0 15 22 22 22 8 8 0 0 % H
% Ile: 8 0 0 8 8 0 0 0 0 0 15 0 0 8 0 % I
% Lys: 8 15 8 8 15 29 0 8 8 22 15 22 0 0 8 % K
% Leu: 0 15 0 8 15 22 36 15 36 0 0 0 8 8 22 % L
% Met: 8 0 0 0 8 0 0 0 0 0 0 8 8 15 22 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % N
% Pro: 8 8 8 15 8 8 0 8 0 8 8 15 29 15 22 % P
% Gln: 8 8 8 0 0 0 0 8 8 15 0 0 8 0 8 % Q
% Arg: 22 0 0 0 8 0 0 0 0 0 8 15 15 22 0 % R
% Ser: 0 15 22 0 0 8 29 22 0 0 0 0 8 8 0 % S
% Thr: 8 22 0 15 29 8 8 0 8 22 22 0 0 0 8 % T
% Val: 0 8 15 22 8 0 8 8 0 0 0 8 0 0 0 % V
% Trp: 15 0 8 0 8 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 15 0 8 15 0 8 0 0 8 0 8 8 15 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _