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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SETD2 All Species: 13.64
Human Site: T2315 Identified Species: 50
UniProt: Q9BYW2 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYW2 NP_054878.5 2564 287550 T2315 V T S P Y S Q T T P P I V Q S
Chimpanzee Pan troglodytes XP_516423 2549 285788 T2300 V T S P Y S Q T T P P I V Q S
Rhesus Macaque Macaca mulatta XP_001113652 2550 286209 T2301 V T S P Y S Q T T P P I V Q S
Dog Lupus familis XP_864158 2562 287091 T2313 V T S P Y S Q T T P P I V Q S
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418510 2354 262767 P2108 P Y S Q T T P P I V Q S Y T Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783359 3042 342758 L2793 Q V L Q T P V L P Q A P Q Q A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q2LAE1 1759 193210 Q1513 N R R F R A S Q E P R Y D H Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 96.9 92 N.A. N.A. N.A. N.A. N.A. 61.7 N.A. N.A. N.A. N.A. N.A. N.A. 24.7
Protein Similarity: 100 98.9 98 94.6 N.A. N.A. N.A. N.A. N.A. 71.5 N.A. N.A. N.A. N.A. N.A. N.A. 41.6
P-Site Identity: 100 100 100 100 N.A. N.A. N.A. N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. N.A. N.A. N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 20.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 15 0 0 0 0 15 0 0 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % E
% Phe: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % H
% Ile: 0 0 0 0 0 0 0 0 15 0 0 58 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 15 0 0 0 0 15 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 15 0 0 58 0 15 15 15 15 72 58 15 0 0 0 % P
% Gln: 15 0 0 29 0 0 58 15 0 15 15 0 15 72 29 % Q
% Arg: 0 15 15 0 15 0 0 0 0 0 15 0 0 0 0 % R
% Ser: 0 0 72 0 0 58 15 0 0 0 0 15 0 0 58 % S
% Thr: 0 58 0 0 29 15 0 58 58 0 0 0 0 15 0 % T
% Val: 58 15 0 0 0 0 15 0 0 15 0 0 58 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 15 0 0 58 0 0 0 0 0 0 15 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _