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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REG4 All Species: 11.21
Human Site: S13 Identified Species: 30.83
UniProt: Q9BYZ8 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYZ8 NP_001152824.1 158 18230 S13 M R L L L L L S C L A K T G V
Chimpanzee Pan troglodytes XP_513694 158 18197 S13 M R L L L L L S C L A K T G V
Rhesus Macaque Macaca mulatta XP_001084012 158 18368 N13 M R L L L L L N C L A K I G V
Dog Lupus familis XP_549465 146 17187 D11 I A F G V C A D I I M R P S C
Cat Felis silvestris
Mouse Mus musculus Q9D8G5 157 18380 S13 V R L L L L L S W V A G P E V
Rat Rattus norvegicus Q68AX7 157 18250 S13 V R L L L L L S W V A G P E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422224 158 18290 C13 C A L L L L C C M V L L P V V
Frog Xenopus laevis NP_001079745 160 18312 A23 V S N V L E A A Q V R S S C P
Zebra Danio Brachydanio rerio NP_001096098 153 17245 F15 L L L L S I V F S M E G A D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 92.4 68.3 N.A. 65.8 66.4 N.A. N.A. 39.8 48.1 36.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 96.8 84.1 N.A. 81.6 79.7 N.A. N.A. 62.6 70.6 52.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 0 N.A. 60 60 N.A. N.A. 33.3 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 26.6 N.A. 73.3 73.3 N.A. N.A. 40 40 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 23 0 0 0 0 23 12 0 0 56 0 12 0 0 % A
% Cys: 12 0 0 0 0 12 12 12 34 0 0 0 0 12 12 % C
% Asp: 0 0 0 0 0 0 0 12 0 0 0 0 0 12 0 % D
% Glu: 0 0 0 0 0 12 0 0 0 0 12 0 0 23 12 % E
% Phe: 0 0 12 0 0 0 0 12 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 12 0 0 0 0 0 0 0 34 0 34 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 0 0 12 0 0 12 12 0 0 12 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 34 0 0 0 % K
% Leu: 12 12 78 78 78 67 56 0 0 34 12 12 0 0 0 % L
% Met: 34 0 0 0 0 0 0 0 12 12 12 0 0 0 0 % M
% Asn: 0 0 12 0 0 0 0 12 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 45 0 12 % P
% Gln: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % Q
% Arg: 0 56 0 0 0 0 0 0 0 0 12 12 0 0 0 % R
% Ser: 0 12 0 0 12 0 0 45 12 0 0 12 12 12 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 23 0 0 % T
% Val: 34 0 0 12 12 0 12 0 0 45 0 0 0 12 67 % V
% Trp: 0 0 0 0 0 0 0 0 23 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _