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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REG4
All Species:
9.09
Human Site:
S52
Identified Species:
25
UniProt:
Q9BYZ8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYZ8
NP_001152824.1
158
18230
S52
F
R
K
L
R
N
W
S
D
A
E
L
E
C
Q
Chimpanzee
Pan troglodytes
XP_513694
158
18197
S52
F
R
K
L
R
N
W
S
D
A
E
L
E
C
Q
Rhesus Macaque
Macaca mulatta
XP_001084012
158
18368
S52
F
R
K
L
R
N
W
S
D
A
E
L
E
C
Q
Dog
Lupus familis
XP_549465
146
17187
G50
E
L
E
C
Q
L
Y
G
N
G
A
H
L
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8G5
157
18380
H52
R
K
L
R
N
W
S
H
A
E
L
E
C
Q
S
Rat
Rattus norvegicus
Q68AX7
157
18250
H52
R
K
L
R
N
W
S
H
A
E
L
E
C
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422224
158
18290
A52
Q
H
R
T
W
E
E
A
E
A
Q
C
Q
N
S
Frog
Xenopus laevis
NP_001079745
160
18312
H62
Y
D
C
Q
A
Y
G
H
G
A
H
L
A
S
I
Zebra Danio
Brachydanio rerio
NP_001096098
153
17245
N54
N
W
V
T
A
E
R
N
C
Q
S
L
G
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
92.4
68.3
N.A.
65.8
66.4
N.A.
N.A.
39.8
48.1
36.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
96.8
84.1
N.A.
81.6
79.7
N.A.
N.A.
62.6
70.6
52.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
0
0
N.A.
N.A.
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
6.6
6.6
N.A.
N.A.
40
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
23
0
0
12
23
56
12
0
12
12
0
% A
% Cys:
0
0
12
12
0
0
0
0
12
0
0
12
23
34
0
% C
% Asp:
0
12
0
0
0
0
0
0
34
0
0
0
0
0
0
% D
% Glu:
12
0
12
0
0
23
12
0
12
23
34
23
34
0
0
% E
% Phe:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
12
12
12
0
0
12
12
0
% G
% His:
0
12
0
0
0
0
0
34
0
0
12
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% I
% Lys:
0
23
34
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
23
34
0
12
0
0
0
0
23
56
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
23
34
0
12
12
0
0
0
0
12
12
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
0
12
12
0
0
0
0
12
12
0
12
23
34
% Q
% Arg:
23
34
12
23
34
0
12
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
23
34
0
0
12
0
0
12
45
% S
% Thr:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
12
0
0
12
23
34
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
12
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _