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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM33
All Species:
8.48
Human Site:
S269
Identified Species:
20.74
UniProt:
Q9BZ11
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZ11
NP_079496.1
813
87739
S269
V
W
T
E
R
D
R
S
R
V
T
Q
D
A
N
Chimpanzee
Pan troglodytes
XP_514485
622
67833
I166
K
D
F
S
T
H
K
I
F
R
M
E
Q
L
L
Rhesus Macaque
Macaca mulatta
XP_001105246
1098
119747
C446
V
W
T
H
G
N
M
C
E
V
S
E
N
P
Y
Dog
Lupus familis
XP_542918
878
94769
S368
V
W
T
E
Q
D
Q
S
R
V
S
P
D
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q923W9
797
86937
S270
V
W
T
E
Q
D
L
S
R
I
T
Q
D
A
N
Rat
Rattus norvegicus
Q9QYV0
816
88034
I273
A
W
T
Q
R
D
L
I
E
M
S
S
N
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507222
856
93750
G241
D
N
A
Q
L
I
T
G
M
S
F
R
G
T
T
Chicken
Gallus gallus
NP_001075887
947
103628
C277
V
W
T
E
R
D
Q
C
T
V
T
S
D
A
N
Frog
Xenopus laevis
NP_001080914
914
99731
C264
V
W
T
E
R
D
Q
C
E
V
N
D
D
A
N
Zebra Danio
Brachydanio rerio
XP_693712
1175
128834
C326
V
W
T
E
H
D
Q
C
I
I
N
E
E
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.9
36.9
67.7
N.A.
70.4
37.5
N.A.
41.7
48.3
45.8
34.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75.1
49
74.3
N.A.
78.4
50
N.A.
55.7
59.9
60.7
46.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
26.6
73.3
N.A.
80
26.6
N.A.
0
73.3
66.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
53.3
93.3
N.A.
93.3
53.3
N.A.
13.3
80
73.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
0
0
0
0
0
0
50
10
% A
% Cys:
0
0
0
0
0
0
0
40
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
70
0
0
0
0
0
10
50
0
0
% D
% Glu:
0
0
0
60
0
0
0
0
30
0
0
30
10
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
10
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
10
0
0
0
0
10
0
0
% G
% His:
0
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
20
10
20
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
20
0
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
10
0
10
10
10
0
0
0
0
% M
% Asn:
0
10
0
0
0
10
0
0
0
0
20
0
20
0
60
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
30
0
% P
% Gln:
0
0
0
20
20
0
40
0
0
0
0
20
10
0
0
% Q
% Arg:
0
0
0
0
40
0
10
0
30
10
0
10
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
30
0
10
30
20
0
0
0
% S
% Thr:
0
0
80
0
10
0
10
0
10
0
30
0
0
10
10
% T
% Val:
70
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% V
% Trp:
0
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _