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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADAM33 All Species: 20.3
Human Site: Y243 Identified Species: 49.63
UniProt: Q9BZ11 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZ11 NP_079496.1 813 87739 Y243 R L L E V A N Y V D Q L L R T
Chimpanzee Pan troglodytes XP_514485 622 67833 I140 C S G M S G L I T L S R N A S
Rhesus Macaque Macaca mulatta XP_001105246 1098 119747 Y420 K L I E I A N Y V D K F Y R S
Dog Lupus familis XP_542918 878 94769 Y342 R L L E V A N Y V D Q I L R T
Cat Felis silvestris
Mouse Mus musculus Q923W9 797 86937 C244 R L L E V A N C V D Q I L R T
Rat Rattus norvegicus Q9QYV0 816 88034 L247 R T L E V A L L L D T F F Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507222 856 93750 S215 N V S E N P Y S T L W S F L S
Chicken Gallus gallus NP_001075887 947 103628 Y251 R I V E I A N Y V D K F Y R L
Frog Xenopus laevis NP_001080914 914 99731 Y238 R V L E I A N Y V D K F Y M S
Zebra Danio Brachydanio rerio XP_693712 1175 128834 Y300 R I M E I A N Y V D K F Y R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.9 36.9 67.7 N.A. 70.4 37.5 N.A. 41.7 48.3 45.8 34.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 75.1 49 74.3 N.A. 78.4 50 N.A. 55.7 59.9 60.7 46.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 53.3 93.3 N.A. 86.6 40 N.A. 6.6 53.3 53.3 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 86.6 100 N.A. 93.3 53.3 N.A. 20 80 80 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 80 0 0 0 0 0 0 0 10 0 % A
% Cys: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 80 0 0 0 0 0 % D
% Glu: 0 0 0 90 0 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 50 20 0 0 % F
% Gly: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 20 10 0 40 0 0 10 0 0 0 20 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 40 0 0 0 0 % K
% Leu: 0 40 50 0 0 0 20 10 10 20 0 10 30 10 10 % L
% Met: 0 0 10 10 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 10 0 0 0 10 0 70 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 30 0 0 10 0 % Q
% Arg: 70 0 0 0 0 0 0 0 0 0 0 10 0 60 0 % R
% Ser: 0 10 10 0 10 0 0 10 0 0 10 10 0 0 40 % S
% Thr: 0 10 0 0 0 0 0 0 20 0 10 0 0 0 30 % T
% Val: 0 20 10 0 40 0 0 0 70 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 60 0 0 0 0 40 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _