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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD8
All Species:
31.21
Human Site:
S199
Identified Species:
62.42
UniProt:
Q9BZ67
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZ67
NP_114110.1
464
51218
S199
D
L
R
E
K
L
D
S
F
L
P
A
H
L
C
Chimpanzee
Pan troglodytes
XP_001169593
464
51164
S199
D
L
R
E
K
L
D
S
F
L
P
A
H
L
C
Rhesus Macaque
Macaca mulatta
XP_001113750
464
51234
S199
A
L
R
E
K
L
D
S
F
L
P
A
H
L
C
Dog
Lupus familis
XP_540860
463
51083
S199
A
L
T
E
K
L
D
S
F
L
P
A
H
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q3UFK8
466
51809
S199
T
L
R
E
K
L
D
S
F
L
P
A
H
L
C
Rat
Rattus norvegicus
Q5U2R3
466
51763
S199
T
V
R
E
K
L
D
S
F
L
P
A
H
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511109
472
52886
S199
A
L
K
E
K
L
D
S
F
L
P
A
H
L
C
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZWP1
452
51566
T197
T
I
R
P
K
L
D
T
L
F
P
P
Y
L
C
Zebra Danio
Brachydanio rerio
XP_687842
471
52209
S201
I
R
E
K
K
L
S
S
F
L
P
A
H
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393357
452
51555
E199
G
A
L
Q
A
R
I
E
L
G
P
Y
N
P
Q
Nematode Worm
Caenorhab. elegans
NP_506340
504
56930
E253
F
I
R
N
H
I
D
E
I
L
P
E
R
T
C
Sea Urchin
Strong. purpuratus
XP_001199223
505
57183
K235
F
F
K
D
N
D
L
K
K
I
L
P
T
C
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.1
86.6
N.A.
87.5
86.6
N.A.
69.4
N.A.
59.2
55.2
N.A.
N.A.
29.5
23
29.7
Protein Similarity:
100
99.5
97.6
92.2
N.A.
92
91.1
N.A.
81.1
N.A.
73.4
68.5
N.A.
N.A.
46.5
41.2
48.1
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
86.6
N.A.
86.6
N.A.
46.6
53.3
N.A.
N.A.
6.6
33.3
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
93.3
N.A.
93.3
N.A.
66.6
60
N.A.
N.A.
20
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
9
0
0
9
0
0
0
0
0
0
67
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
75
% C
% Asp:
17
0
0
9
0
9
75
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
59
0
0
0
17
0
0
0
9
0
0
0
% E
% Phe:
17
9
0
0
0
0
0
0
67
9
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
67
0
0
% H
% Ile:
9
17
0
0
0
9
9
0
9
9
0
0
0
0
0
% I
% Lys:
0
0
17
9
75
0
0
9
9
0
0
0
0
0
0
% K
% Leu:
0
50
9
0
0
75
9
0
17
75
9
0
0
67
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
9
9
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
92
17
0
9
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
9
59
0
0
9
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
0
0
0
0
0
9
67
0
0
0
0
0
0
0
% S
% Thr:
25
0
9
0
0
0
0
9
0
0
0
0
9
9
0
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _