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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD8
All Species:
26.67
Human Site:
S326
Identified Species:
53.33
UniProt:
Q9BZ67
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZ67
NP_114110.1
464
51218
S326
E
L
S
W
D
H
T
S
P
E
E
E
E
P
I
Chimpanzee
Pan troglodytes
XP_001169593
464
51164
S326
E
L
S
W
D
H
T
S
P
E
E
E
E
P
I
Rhesus Macaque
Macaca mulatta
XP_001113750
464
51234
S326
E
L
S
W
D
H
T
S
P
E
E
E
E
P
I
Dog
Lupus familis
XP_540860
463
51083
S325
E
L
S
W
D
H
T
S
P
E
E
E
E
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3UFK8
466
51809
S327
E
L
S
W
D
H
T
S
P
E
E
E
E
P
V
Rat
Rattus norvegicus
Q5U2R3
466
51763
S327
E
L
S
W
D
H
T
S
P
E
E
E
E
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511109
472
52886
E328
E
L
S
W
D
H
T
E
P
R
V
E
S
F
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZWP1
452
51566
Y315
H
V
L
I
S
L
T
Y
P
E
L
S
W
D
H
Zebra Danio
Brachydanio rerio
XP_687842
471
52209
Y327
E
L
S
W
D
H
S
Y
P
E
T
E
G
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393357
452
51555
M310
S
W
I
T
N
R
D
M
Y
I
L
I
A
I
N
Nematode Worm
Caenorhab. elegans
NP_506340
504
56930
L364
E
S
N
S
G
T
L
L
V
H
P
L
E
E
L
Sea Urchin
Strong. purpuratus
XP_001199223
505
57183
E353
E
L
S
W
E
F
T
E
P
A
R
K
E
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.1
86.6
N.A.
87.5
86.6
N.A.
69.4
N.A.
59.2
55.2
N.A.
N.A.
29.5
23
29.7
Protein Similarity:
100
99.5
97.6
92.2
N.A.
92
91.1
N.A.
81.1
N.A.
73.4
68.5
N.A.
N.A.
46.5
41.2
48.1
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
60
N.A.
20
60
N.A.
N.A.
0
13.3
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
60
N.A.
26.6
66.6
N.A.
N.A.
6.6
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
67
0
9
0
0
0
0
0
0
17
9
% D
% Glu:
84
0
0
0
9
0
0
17
0
67
50
67
67
9
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% G
% His:
9
0
0
0
0
67
0
0
0
9
0
0
0
0
9
% H
% Ile:
0
0
9
9
0
0
0
0
0
9
0
9
0
9
25
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
75
9
0
0
9
9
9
0
0
17
9
0
0
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
84
0
9
0
0
42
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
9
9
0
0
0
0
% R
% Ser:
9
9
75
9
9
0
9
50
0
0
0
9
9
9
9
% S
% Thr:
0
0
0
9
0
9
75
0
0
0
9
0
0
0
0
% T
% Val:
0
9
0
0
0
0
0
0
9
0
9
0
0
9
25
% V
% Trp:
0
9
0
75
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
17
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _