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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FRMD8 All Species: 12.42
Human Site: S393 Identified Species: 24.85
UniProt: Q9BZ67 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZ67 NP_114110.1 464 51218 S393 G S P S D P S S S L A P V Q R
Chimpanzee Pan troglodytes XP_001169593 464 51164 S393 G S P S D P S S S P A P V Q R
Rhesus Macaque Macaca mulatta XP_001113750 464 51234 S393 G P P S D P S S S P A P V E R
Dog Lupus familis XP_540860 463 51083 A392 G T P S A A G A P P P P I Q R
Cat Felis silvestris
Mouse Mus musculus Q3UFK8 466 51809 P394 G P H E A P S P S P P P T Q R
Rat Rattus norvegicus Q5U2R3 466 51763 P394 G P Q E A P S P S S A P T Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511109 472 52886 P401 A G V T N P Q P P S T V P Q R
Chicken Gallus gallus
Frog Xenopus laevis Q7ZWP1 452 51566 T381 E S P A S D S T P G N S Q L S
Zebra Danio Brachydanio rerio XP_687842 471 52209 T396 V T P S H E P T S P E T N N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393357 452 51555 L376 G T Q V Y K I L Q V F S R Q A
Nematode Worm Caenorhab. elegans NP_506340 504 56930 T432 D A L L K T M T G R R L D R S
Sea Urchin Strong. purpuratus XP_001199223 505 57183 L424 H T V M G G L L S N E N N S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97.1 86.6 N.A. 87.5 86.6 N.A. 69.4 N.A. 59.2 55.2 N.A. N.A. 29.5 23 29.7
Protein Similarity: 100 99.5 97.6 92.2 N.A. 92 91.1 N.A. 81.1 N.A. 73.4 68.5 N.A. N.A. 46.5 41.2 48.1
P-Site Identity: 100 93.3 80 40 N.A. 46.6 53.3 N.A. 20 N.A. 20 20 N.A. N.A. 13.3 0 6.6
P-Site Similarity: 100 93.3 86.6 60 N.A. 46.6 53.3 N.A. 33.3 N.A. 33.3 40 N.A. N.A. 26.6 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 9 25 9 0 9 0 0 34 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 25 9 0 0 0 0 0 0 9 0 0 % D
% Glu: 9 0 0 17 0 9 0 0 0 0 17 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 59 9 0 0 9 9 9 0 9 9 0 0 0 0 0 % G
% His: 9 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 0 % I
% Lys: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 9 % K
% Leu: 0 0 9 9 0 0 9 17 0 9 0 9 0 9 0 % L
% Met: 0 0 0 9 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 9 9 9 17 9 0 % N
% Pro: 0 25 50 0 0 50 9 25 25 42 17 50 9 0 0 % P
% Gln: 0 0 17 0 0 0 9 0 9 0 0 0 9 59 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 9 0 9 9 59 % R
% Ser: 0 25 0 42 9 0 50 25 59 17 0 17 0 9 25 % S
% Thr: 0 34 0 9 0 9 0 25 0 0 9 9 17 0 0 % T
% Val: 9 0 17 9 0 0 0 0 0 9 0 9 25 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _