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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD8
All Species:
27.88
Human Site:
S408
Identified Species:
55.76
UniProt:
Q9BZ67
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZ67
NP_114110.1
464
51218
S408
P
K
L
R
R
Q
G
S
V
V
S
S
R
I
Q
Chimpanzee
Pan troglodytes
XP_001169593
464
51164
S408
P
K
L
R
R
Q
G
S
V
V
S
S
R
I
Q
Rhesus Macaque
Macaca mulatta
XP_001113750
464
51234
S408
P
K
L
R
R
Q
G
S
V
V
S
S
R
I
Q
Dog
Lupus familis
XP_540860
463
51083
S407
P
Q
L
R
R
Q
G
S
V
V
C
S
R
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3UFK8
466
51809
S409
P
K
L
R
R
Q
G
S
V
V
C
S
R
I
Q
Rat
Rattus norvegicus
Q5U2R3
466
51763
S409
P
K
L
R
R
Q
G
S
V
V
C
S
R
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511109
472
52886
S416
H
K
L
R
R
Q
G
S
V
I
C
S
R
I
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZWP1
452
51566
R396
E
K
R
S
K
L
K
R
Q
E
S
V
L
C
N
Zebra Danio
Brachydanio rerio
XP_687842
471
52209
K411
T
R
E
R
R
Q
G
K
L
R
R
Q
N
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393357
452
51555
S391
I
M
M
D
I
L
I
S
G
F
A
E
E
H
R
Nematode Worm
Caenorhab. elegans
NP_506340
504
56930
S447
S
S
D
S
S
S
S
S
D
S
S
T
S
S
T
Sea Urchin
Strong. purpuratus
XP_001199223
505
57183
D439
T
V
N
Q
D
E
P
D
A
P
M
S
P
H
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.1
86.6
N.A.
87.5
86.6
N.A.
69.4
N.A.
59.2
55.2
N.A.
N.A.
29.5
23
29.7
Protein Similarity:
100
99.5
97.6
92.2
N.A.
92
91.1
N.A.
81.1
N.A.
73.4
68.5
N.A.
N.A.
46.5
41.2
48.1
P-Site Identity:
100
100
100
80
N.A.
93.3
93.3
N.A.
80
N.A.
13.3
26.6
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
N.A.
20
40
N.A.
N.A.
26.6
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
34
0
0
9
0
% C
% Asp:
0
0
9
9
9
0
0
9
9
0
0
0
0
0
0
% D
% Glu:
9
0
9
0
0
9
0
0
0
9
0
9
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
67
0
9
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% H
% Ile:
9
0
0
0
9
0
9
0
0
9
0
0
0
50
0
% I
% Lys:
0
59
0
0
9
0
9
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
59
0
0
17
0
0
9
0
0
0
9
9
0
% L
% Met:
0
9
9
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
9
% N
% Pro:
50
0
0
0
0
0
9
0
0
9
0
0
9
0
0
% P
% Gln:
0
9
0
9
0
67
0
0
9
0
0
9
0
0
59
% Q
% Arg:
0
9
9
67
67
0
0
9
0
9
9
0
59
0
17
% R
% Ser:
9
9
0
17
9
9
9
75
0
9
42
67
9
17
0
% S
% Thr:
17
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% T
% Val:
0
9
0
0
0
0
0
0
59
50
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _