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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD8
All Species:
27.58
Human Site:
S442
Identified Species:
55.15
UniProt:
Q9BZ67
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZ67
NP_114110.1
464
51218
S442
K
R
T
T
S
F
F
S
R
Q
L
S
L
G
Q
Chimpanzee
Pan troglodytes
XP_001169593
464
51164
S442
K
R
T
T
S
F
F
S
R
Q
L
S
L
G
Q
Rhesus Macaque
Macaca mulatta
XP_001113750
464
51234
S442
K
R
T
T
S
F
F
S
R
Q
L
S
L
G
Q
Dog
Lupus familis
XP_540860
463
51083
S441
K
R
T
T
S
F
F
S
R
Q
L
S
M
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3UFK8
466
51809
S443
K
R
T
T
S
F
F
S
R
Q
L
S
S
S
Q
Rat
Rattus norvegicus
Q5U2R3
466
51763
S443
K
R
T
T
S
F
F
S
R
Q
L
S
S
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511109
472
52886
S450
K
R
T
T
S
F
F
S
R
Q
L
S
L
G
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZWP1
452
51566
S430
V
K
P
K
R
T
A
S
F
F
T
R
Q
N
T
Zebra Danio
Brachydanio rerio
XP_687842
471
52209
R445
I
K
R
L
K
P
K
R
A
A
S
F
F
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393357
452
51555
T425
G
S
N
I
G
S
F
T
N
K
L
S
K
F
T
Nematode Worm
Caenorhab. elegans
NP_506340
504
56930
K481
N
R
K
L
C
F
A
K
F
K
D
G
K
C
T
Sea Urchin
Strong. purpuratus
XP_001199223
505
57183
D473
T
G
L
C
S
K
M
D
R
L
C
L
S
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.1
86.6
N.A.
87.5
86.6
N.A.
69.4
N.A.
59.2
55.2
N.A.
N.A.
29.5
23
29.7
Protein Similarity:
100
99.5
97.6
92.2
N.A.
92
91.1
N.A.
81.1
N.A.
73.4
68.5
N.A.
N.A.
46.5
41.2
48.1
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
93.3
N.A.
6.6
0
N.A.
N.A.
20
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
80
N.A.
93.3
N.A.
13.3
13.3
N.A.
N.A.
33.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
17
0
9
9
0
0
0
0
0
% A
% Cys:
0
0
0
9
9
0
0
0
0
0
9
0
0
9
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
67
67
0
17
9
0
9
9
9
9
% F
% Gly:
9
9
0
0
9
0
0
0
0
0
0
9
0
42
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
59
17
9
9
9
9
9
9
0
17
0
0
17
0
0
% K
% Leu:
0
0
9
17
0
0
0
0
0
9
67
9
34
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% M
% Asn:
9
0
9
0
0
0
0
0
9
0
0
0
0
9
0
% N
% Pro:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
59
0
0
9
0
42
% Q
% Arg:
0
67
9
0
9
0
0
9
67
0
0
9
0
0
9
% R
% Ser:
0
9
0
0
67
9
0
67
0
0
9
67
25
17
0
% S
% Thr:
9
0
59
59
0
9
0
9
0
0
9
0
0
17
34
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _